Photoacoustic-based catheter tracking: simulation, phantom, and in vivo studies
Photoacoustic-based catheter tracking: simulation, phantom, and in vivo studies
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DOI：
10.1117/1.jmi.5.2.021223
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发表时间：
2018-04-01
影响因子：
2.4
通讯作者：
Boctor, Emad M.
中科院分区：
文献类型：
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作者：
Cheng, Alexis;Kim, Younsu;Boctor, Emad M.
导管通常用于许多手术，跟踪和定位它们对患者安全和手术成功至关重要。导管跟踪的标准护理是使用荧光透视。先前已经探索了使用诸如电磁跟踪器的常规跟踪技术的替代方案。这项工作探讨了使用新兴的成像方式，光声，作为一种手段进行跟踪。压电（PZT）传感器放置在导管的尖端，使其能够接收由于光声效应而从光声标记产生的声信号。这些光声标记的位置由立体相机确定，并且接收到的声学信号被转换成PZT元件与光声标记之间的距离。PZT传感器的位置可以在简化过程之后唯一地确定。这项工作验证了这种光声跟踪方法在幻影，模拟，并在体内的情况下使用的指标，包括重建精度，相对精度，估计精度，和遗漏的准确性。在体模实验中实现了亚毫米波跟踪结果。模拟研究评估了与光声源和PZT传感器相关的各种物理参数。体内结果显示了该技术最终部署的可行性。(c)2018年，摄影光学仪器工程师协会（SPIE）
Catheters are commonly used in many procedures and tracking and localizing them is critical to patient safety and surgical success. The standard of care for catheter tracking is with the use of fluoroscopy. Alternatives using conventional tracking technologies such as electromagnetic trackers have been previously explored. This work explores the use of an emerging imaging modality, photoacoustics, as a means for tracking. A piezoelectric (PZT) sensor is placed at the tip of the catheter, allowing it to receive the acoustic signals generated from photoacoustic markers due to the photoacoustic effect. The locations of these photoacoustic markers are determined by a stereo-camera and the received acoustic signals are converted into distances between the PZT element and the photoacoustic markers. The location of the PZT sensor can be uniquely determined following a multilateration process. This work validates this photoacoustic tracking method in phantom, simulation, and in vivo scenarios using metrics including reconstruction precision, relative accuracy, estimated accuracy, and leave-out accuracy. Submillimeter tracking results were achieved in phantom experiments. Simulation studies evaluated various physical parameters relating to the photoacoustic source and the PZT sensor. In vivo results showed feasibility for the eventual deployment of this technology. (c) 2018 Society of Photo-Optical Instrumentation Engineers (SPIE)