Dehydration confounds the assessment of brain atrophy
Dehydration confounds the assessment of brain atrophy
复制标题
DOI：
10.1212/01.wnl.0000150542.16969.cc
复制
发表时间：
2005-02-08
期刊：
影响因子：
9.9
通讯作者：
Knecht, S
中科院分区：
文献类型：
--
作者：
Duning, T;Kloska, S;Knecht, S
计算机脑容量测定对退行性疾病的诊断和随访评估具有潜在价值。这种方法的一个潜在缺陷是脑容量的生理变化程度。作者表明，脱水和再水化可以显著改变脑容量：缺乏液体摄入16小时使脑容量减少0.55%（SD，+/-0.69），再水化后总脑容量增加0.72%（SD，+/-0.21）。
Computerized brain volumetry has potential value for diagnosis and the follow-up evaluation of degenerative disorders. A potential pitfall of this method is the extent of physiologic variations in brain volume. The authors show that dehydration and rehydration can significantly change brain volume: lack of fluid intake for 16 hours decreased brain volume by 0.55% (SD, +/-0.69), and after rehydration total cerebral volume increased by 0.72% (SD, +/-0.21).