THE PREVALENCE OF ORAL LESIONS IN HIV-INFECTED HOMOSEXUAL AND BISEXUAL MEN - 3 SAN-FRANCISCO EPIDEMIOLOGIC COHORTS
THE PREVALENCE OF ORAL LESIONS IN HIV-INFECTED HOMOSEXUAL AND BISEXUAL MEN - 3 SAN-FRANCISCO EPIDEMIOLOGIC COHORTS
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DOI：
10.1097/00002030-199105000-00007
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发表时间：
1991-05-01
期刊：
影响因子：
3.8
通讯作者：
GREENSPAN, JS
中科院分区：
文献类型：
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作者：
FEIGAL, DW;KATZ, MH;GREENSPAN, JS
为了确定与 HIV 相关的口腔病变的患病率，我们在 3 年的时间里对旧金山的三个同性恋和双性恋男性流行病学队列的成员进行了口腔检查。 毛状白斑、假膜性和红斑念珠菌病、口角炎、卡波西肉瘤和口腔溃疡在 HIV 感染者中比 HIV 阴性者更常见。 在 HIV 感染者中，毛状白斑是最常见的病变 [20.4%，95% 置信区间 (Cl) 17.5-23.3%]，假膜念珠菌病是第二常见的病变 (5.8%，95% CI 4.1-7.5%)。 毛状白斑、假膜性念珠菌病、口角炎和卡波西肉瘤在 CD4 淋巴细胞计数较低的患者中更为常见（P < 0.05）。 红斑念珠菌病和卡波西肉瘤的患病率在三年期间有所增加。 仔细的口腔检查可以识别感染的患者并提供有关其免疫状态的提示性信息。
To establish the prevalence of HIV-related oral lesions, we performed oral examinations of members of three San Francisco epidemiological cohorts of homosexual and bisexual men over a 3-year period. Hairy leukoplakia, pseudomembranous and erythematous candidiasis, angular cheilitis, Kaposi's sarcoma, and oral ulcers were more common in HIV-infected subjects than in HIV-negative subjects. Among HIV-infected individuals, hairy leukoplakia was the most common lesion [20.4%, 95% confidence interval (Cl) 17.5-23.3%] and pseudomembranous candidiasis was the next most common (5.8%, 95% Cl 4.1-7.5%). Hairy leukoplakia, pseudomembranous candidiasis, angular cheilitis and Kaposi's sarcoma were significantly more common in patients with lower CD4 lymphocyte counts (P < 0.05). The prevalence of erythematous candidiasis and Kaposi's sarcoma increased during the 3-year period. Careful oral examinations may identify infected patients and provide suggestive information concerning their immune status.