The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure.
The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure.
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作者：
Polhemus DJ;Calvert JW;Butler J;Lefer DJ
硫化氢(H_2S)以前只被认为是一种致命的毒素，但它在多个器官系统中具有强大的细胞保护作用，这一点现在已被普遍接受。不同的硫化氢信号转导通路在多种病理状态下发挥细胞保护作用。本文就近年来硫化氢在心肌缺血再灌注损伤和充血性心力衰竭中的心脏保护作用作一综述。
It has now become universally accepted that hydrogen sulfide (H2S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H2S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure.