SEQUENCE OF 2 MESSENGER-RNAS ENCODING ACTIVE-RAT TRYPTOPHAN-HYDROXYLASE
SEQUENCE OF 2 MESSENGER-RNAS ENCODING ACTIVE-RAT TRYPTOPHAN-HYDROXYLASE
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DOI：
10.1111/j.1471-4159.1988.tb04871.x
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发表时间：
1988-07-01
影响因子：
4.7
通讯作者：
MALLET, J
中科院分区：
文献类型：
--
作者：
DARMON, MC;GUIBERT, B;MALLET, J
从大鼠松果体文库中分离到两个编码5-羟色胺合成关键酶色氨酸羟化酶（EC 1.14.16.4）的全长cDNA克隆。这两个克隆分别对应于1.8-和4-脱氢酶mRNA种类。它们含有对应于51，010-道尔顿蛋白的相同编码序列，并且它们的3“非翻译区的长度不同。
Two full-length cDNA clones that encode functional rat tryptophan hydroxylase (EC 1.14.16.4), the key enzyme in serotonin synthesis, have been isolated from a rat pineal gland library. These two clones correspond to the 1.8- and 4-kilobase mRNA species, respectively. They contain the same coding sequence corresponding to a 51,010-dalton protein and differ in the length of their 3'' untranslated regions.