CALCULATION OF THE UNCERTAINTY IN THE DOSE DELIVERED DURING RADIATION-THERAPY
CALCULATION OF THE UNCERTAINTY IN THE DOSE DELIVERED DURING RADIATION-THERAPY
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DOI：
10.1118/1.595762
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发表时间：
1985-01-01
期刊：
影响因子：
3.8
通讯作者：
GOITEIN, M
中科院分区：
文献类型：
--
作者：
GOITEIN, M
不可避免的是，我们对受照患者体内任何时间点的剂量的了解都存在不确定性。提出了一种通过执行三次并行计算来估计这种不确定度的技术，一次使用与剂量相关的参数的标称值，另一次使用极值。这种计算几乎可以用任何计算剂量的算法进行。它们导致在某个由所用数据确定的特定置信度下，对任何时间点可能的剂量范围进行估计。这样的计算应该有助于治疗师避免过量或不足的剂量，这在常规的名义剂量计算中可能并不明显。
There is, inevitably, uncertainty in our knowledge of the dose at any point within an irradiated patient. A technique is presented for estimating this uncertainty by performing three parallel calculations, one using nominal values and the others extreme values of the parameters upon which the dose depends. Such calculations can be made with almost any algorithm for calculating dose. They result in an estimate, at some specified confidence level which is determined by the data used, of the range of dose likely at any point. Such calculations should help therapists to avert over- or underdosage which might not be evident in conventional calculations of the nominal dose.