Investigating mental defeat in individuals with chronic pain: Protocol for a longitudinal experience sampling study.

Investigating mental defeat in individuals with chronic pain: Protocol for a longitudinal experience sampling study.
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DOI:
10.1136/bmjopen-2022-066577
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发表时间:
2023-02-06
期刊:
影响因子:
2.9
通讯作者:
--
中科院分区:
医学3区
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--
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以前的定性和横断面研究已经确定了慢性疼痛患者的强烈精神挫败感,他们也经历了最大程度的痛苦和残疾。本研究将采用纵向经验抽样设计,探讨慢性疼痛相关的精神挫败感和痛苦感与残疾之间的人内联系。我们的目标是招募198名患有慢性疼痛的参与者(年龄18-65岁),在1周内完成两波经验采样,间隔6个月(时间1和时间2)。在每一波体验采样期间,参与者被要求每天完成三次简短的在线调查,使用视觉模拟量表提供精神挫败,疼痛,药物使用,身体和社会活动,压力,情绪,自我同情和注意力的即时评级。睡眠和身体活动将使用每日日记以及参与者在每个波中连续佩戴的腕动计来测量。线性混合模型和高斯图形模型将与数据拟合,以:(1)检查心理失败与结果的个人内部、日常联系(即,疼痛、身体/社会活动、药物使用和睡眠),(2)检查具有所有结果的精神失败的动态时间和同期网络以及结果的假设机制(即感知压力、情绪、注意力和自我同情)。当前方案已获得卫生研究机构和West Midlands-Solihull研究伦理委员会的批准(参考编号:17/WM 0053)。本研究按照赫尔辛基宣言、沃里克标准操作规程和适用的英国立法进行。
Previous qualitative and cross-sectional research has identified a strong sense of mental defeat in people with chronic pain who also experience the greatest levels of distress and disability. This study will adopt a longitudinal experience sampling design to examine the within-person link between the sense of mental defeat and distress and disability associated with chronic pain. We aim to recruit 198 participants (aged 18–65 years) with chronic pain, to complete two waves of experience sampling over 1 week, 6 months apart (time 1 and time 2). During each wave of experience sampling, the participants are asked to complete three short online surveys per day, to provide in-the-moment ratings of mental defeat, pain, medication usage, physical and social activity, stress, mood, self-compassion, and attention using visual analogue scales. Sleep and physical activity will be measured using a daily diary as well as with wrist actigraphy worn continuously by participants throughout each wave. Linear mixed models and Gaussian graphical models will be fit to the data to: (1) examine the within-person, day-to-day association of mental defeat with outcomes (ie, pain, physical/social activity, medication use and sleep), (2) examine the dynamic temporal and contemporaneous networks of mental defeat with all outcomes and the hypothesised mechanisms of outcomes (ie, perceived stress, mood, attention and self-compassion). The current protocol has been approved by the Health Research Authority and West Midlands—Solihull Research Ethics Committee (Reference Number: 17/WM0053). The study is being conducted in adherence with the Declaration of Helsinki, Warwick Standard Operating Procedures and applicable UK legislation.
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