Striatal 123 I-2β-carbomethoxy-3b-(4-iodophenyl)-N-(3-fluoropropyl)-nortropane single-photon emission computed tomography demonstrates nigral degeneration in the early stage of behavioural variant frontotemporal dementia: an autopsy case with frontotempor

Striatal 123 I-2β-carbomethoxy-3b-(4-iodophenyl)-N-(3-fluoropropyl)-nortropane single-photon emission computed tomography demonstrates nigral degeneration in the early stage of behavioural variant frontotemporal dementia: an autopsy case with frontotempor
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纹状体 123 I-2β-甲甲氧基-3b-(4-碘苯基)-N-(3-氟丙基)-去托烷单光子发射计算机断层扫描显示行为变异型额颞叶痴呆早期黑质变性:额颞叶尸检病例

DOI:
10.1111/psyg.12842
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发表时间:
2022
期刊:
影响因子:
2
通讯作者:
Ozaki Norio
Ozaki Norio
中科院分区:
医学4区
文献类型:
--
作者:
Arafuka Shusei;Fujishiro Hiroshige;Iritani Shuji;Torii Youta;Miwa Ayako;Yabata Hiroyuki;Sekiguchi Hirotaka;Habuchi Chikako;Kawashima Kunihiro;Yoshida Mari;Iwasaki Yasushi;Ozaki Norio

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该文章介绍了一名 52 岁男子的病例报告,该男子有社交不当和冷漠行为。检查显示双侧额叶萎缩和灌注不足,他被诊断患有行为​​变异型额颞叶痴呆(bvFTD)。他在 55 岁时出现吞咽困难,十个月后死于反复吸入性肺炎。还值得注意的是在额颞叶变性 (FTLD)-TDP B 型患者中检测到异常多巴胺转运蛋白 (DAT)。
The article presents a case report of a 52-year-old man with socially inappropriate and apathetic behaviours. Examinations showed bilateral frontal lobes with atrophy and hypoperfusion and he was diagnosed with behavioural variant frontotemporal dementia (bvFTD). He developed dysphagia at age 55 and ten months hence, died of repeated aspiration pneumonia. Also noted is the detection of abnormal dopamine transporter (DAT) findings in frontotemporal lobar degeneration (FTLD)-TDP type B patients.