New Therapies in SLE
New Therapies in SLE
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DOI：
10.2174/187221308783399243
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发表时间：
2008-01-01
影响因子：
4.2
通讯作者：
La Cava, Antonio
中科院分区：
文献类型：
--
作者：
Ferrera, Francesca;Filaci, Gilberto;La Cava, Antonio
系统性红斑狼疮(SLE)是一种病因不明的全身性自身免疫性疾病，其治疗因疾病表现的多样性和多种复杂的免疫异常而显著复杂化。最近的临床前研究显示了几种药物和/或新化合物的治疗效果，其中一些已经在临床试验中进行了测试。本文综述了系统性红斑狼疮的新治疗方法的最新应用，以及可发展为临床治疗的新疗法的最新专利。
The therapy of systemic lupus erythematosus (SLE), a systemic autoimmune disease of unknown aetiology, is significantly complicated by the diversity of disease manifestations and by a variety of complex immune abnormalities. Recent preclinical studies have shown the therapeutic efficacy of several drugs and/or new compounds, some of which have been tested in clinical trials. This review provides an update on the use of new approaches in SLE and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the management of the disease.