Evaluation of angiogenesis and perfusion of bone marrow lesions: Role of semiquantitative and quantitative dynamic MRI
Evaluation of angiogenesis and perfusion of bone marrow lesions: Role of semiquantitative and quantitative dynamic MRI
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DOI：
10.1002/(sici)1522-2586(199909)10:3
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发表时间：
1999-09
影响因子：
4.4
通讯作者：
H. Hawighorst;M. Libicher;M. Knopp;T. Moehler;G. Kauffmann;G. Kaick
中科院分区：
文献类型：
--
作者：
H. Hawighorst;M. Libicher;M. Knopp;T. Moehler;G. Kauffmann;G. Kaick
磁共振成像（MRI）是一种非侵入性技术，通过采集大量肌肉骨骼样本并提供有助于各种病变诊断、分期和随访的信息，补充计算机断层扫描（CT）、传统X线和骨髓活检。虽然对骨的矿物质成分不太敏感，但生理骨髓的MRI表现主要反映了红骨髓、黄骨髓和骨小梁的相对量。因此，使用T1和T2加权MR序列（有或无脂肪抑制）目前仍然是肌肉骨骼病变成像的最常见方法。表征各种骨病变的另一种成像策略是应用对比增强动态MRI。本文探讨了各种良性和恶性肌肉骨骼病变的半定量和定量动态成像，评价和后处理技术。提出了进行动态对比增强MR检查的实用指南。J.磁共振成像1999; 10：286-294.© 1999 Wiley利斯公司
Magnetic resonance imaging (MRI) is a noninvasive technique that complements computed tomography (CT), conventional X‐ray, and bone marrow biopsies by sampling a large volume of musculoskeletal bone and providing information that aids the diagnosis, staging, and follow‐up of various lesions. Although less sensitive to the mineral components of bones, the MRI appearance of physiologic bone marrow is mainly a reflection of the relative amounts of red marrow, yellow marrow, and trabecular bone. Therefore, use of T1‐and T2‐weighted MR sequences with or without fat suppression currently remains the most common approach to musculoskeletal bone lesion imaging. An additional imaging strategy to characterize various bone lesions is the application of contrast‐enhanced dynamic MRI. This article examines semiquantitative and quantitative dynamic imaging, evaluation, and postprocessing techniques in various benign and malignant musculoskeletal lesions. Practical guidelines for performing a dynamic contrast‐enhanced MR examination are proposed. J. Magn. Reson. Imaging 1999; 10:286–294. © 1999 Wiley‐Liss, Inc.