Cell biology: Centromere instability and replication stress underlie Xenopus hybrid incompatibility.
Cell biology: Centromere instability and replication stress underlie Xenopus hybrid incompatibility.
复制标题
细胞生物学：着丝粒不稳定和复制应激是非洲爪蟾杂交不相容性的基础。
DOI：
10.1016/j.cub.2022.08.015
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Mellone,BarbaraG
中科院分区：
文献类型：
--
作者：
Santinello,Bryce;Mellone,BarbaraG
近亲青蛙之间的杂交会产生无法存活的胚胎，这些胚胎会在灾难性的细胞分裂后死亡。一项新的研究确定了着丝粒维持和DNA复制应激的缺陷是驱动这种不相容性的关键因素。
Crosses between closely related species of frogs result in inviable embryos that die following catastrophic cell divisions. A new study identifies defects in centromere maintenance and DNA replication stress as key forces driving this incompatibility.