Delay Discounting as a Transdiagnostic Process in Psychiatric Disorders A Meta-analysis

Delay Discounting as a Transdiagnostic Process in Psychiatric Disorders A Meta-analysis
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DOI:
10.1001/jamapsychiatry.2019.2102
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发表时间:
2019-11-01
期刊:
影响因子:
25.8
通讯作者:
McCabe, Randi E.
McCabe, Randi E.
中科院分区:
医学1区
文献类型:
--
作者:
Amlung, Michael;Marsden, Emma;McCabe, Randi E.

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延迟折扣是一种行为经济学指标,反映了人们对较小的即时奖励或较大的延迟奖励的冲动偏好,被认为是一种跨健康状况的诊断过程。研究表明,一些精神疾病与折扣与对照组相比的差异有关,但也有无效的结果reported.Objective进行荟萃分析的已发表文献延迟折扣在精神疾病的人。数据来源PubMed,MEDLINE,PsycInfo,Embase和Web of Science数据库检索到2018年12月10日。使用的精神病学关键词基于DSM-IV或DSM-5诊断类别。收集的数据分析时间为2018年12月10日至2019年6月1日。研究选择按照预先注册的系统评价和荟萃分析首选报告项目(PRISMA)方案,由2名独立评分员对标题、摘要和全文文章进行审查。英文的文章比较货币延迟折扣与精神疾病和controls.DATA提取和综合的参与者之间进行了计算对冲效应大小和随机效应模型用于所有的分析。异方差统计,一项研究删除分析,出版偏倚indexs.Main结果和措施之间的精神病组和对照group.RESULTS的延迟折扣的分类比较样本包括57个效果大小的43项研究在8个诊断类别。与对照组相比,患有精神障碍的个体在重度抑郁症(Hedges g=0.37; P= 0.002; k=7)、精神分裂症(Hedges g=0.46; P = 0.004; k = 12)、边缘型人格障碍(Hedges g= 0.60; P = 0.004; k=12)、精神分裂症(Hedges g=0.46; P= 0.004; k=12)、精神分裂症(Hedges g=0.46; P= 0.004; k=12)、精神分裂症(Hedges g= 0.46; P = 0.004; k = 12)和边缘型人格障碍(Hedges g=0.60; P = 0.001; k = 0.001)中的折扣显著更大。
IMPORTANCE Delay discounting is a behavioral economic index of impulsive preferences for smaller-immediate or larger-delayed rewards that is argued to be a transdiagnostic process across health conditions. Studies suggest some psychiatric disorders are associated with differences in discounting compared with controls, but null findings have also been reported.OBJECTIVE To conduct a meta-analysis of the published literature on delay discounting in people with psychiatric disorders.DATA SOURCES PubMed, MEDLINE, PsycInfo, Embase, and Web of Science databases were searched through December 10, 2018. The psychiatric keywords used were based on DSM-IV or DSM-5 diagnostic categories. Collected data were analyzed from December 10, 2018, through June 1, 2019.STUDY SELECTION Following a preregistered Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol, 2 independent raters reviewed titles, abstracts, and full-text articles. English-language articles comparing monetary delay discounting between participants with psychiatric disorders and controls were included.DATA EXTRACTION AND SYNTHESIS Hedges g effect sizes were computed and random-effects models were used for all analyses. Heterogeneity statistics, one-study-removed analyses, and publication bias indices were also examined.MAIN OUTCOMES AND MEASURES Categorical comparisons of delay discounting between a psychiatric group and a control group.RESULTS The sample included 57 effect sizes from 43 studies across 8 diagnostic categories. Significantly steeper discounting for individuals with a psychiatric disorder compared with controls was observed for major depressive disorder (Hedges g=0.37; P=.002; k=7), schizophrenia (Hedges g=0.46; P=.004; k=12), borderline personality disorder (Hedges g=0.60; P