A Decade of Treatment of Canine Parvovirus in an Animal Shelter: A Retrospective Study
A Decade of Treatment of Canine Parvovirus in an Animal Shelter: A Retrospective Study
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动物收容所治疗犬细小病毒的十年历程： 回顾性研究
DOI：
10.3390/ani10060939
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发表时间：
2020-06-01
期刊：
影响因子：
3
通讯作者：
Jefferson, Ellen
中科院分区：
文献类型：
--
作者：
Horecka, Kevin;Porter, Steve;Jefferson, Ellen
犬细小病毒（CPV）是一种高度传染性的胃肠道疾病，影响未接种疫苗，接种不足或接种不当的犬，如果不治疗，死亡率超过90%。私人诊所的治疗费用通常高达数千美元，这使得许多宠物主人无法负担，也使得收容所的治疗面临挑战。在这里，我们检查了11.5年的数据从奥斯汀宠物活着！，德克萨斯州奥斯汀的一家私人动物收容所，自2008年以来已经治疗了5127只感染CPV的狗。我们显示了86.6%（n= 4438/5127）的存活率，在护理的前五天是治疗的最关键时期，并详细说明了用于实现这一高比例成功治疗结果的方案。观察到CPV季节在5月和6月达到高峰，与8月、9月、12月和1月的低水平期相比，每月增加41只动物。低体重动物和雄性动物的死亡风险较高。总之，这些结果旨在帮助庇护所制定治疗这种疾病的计划，并激励未来的研究改进治疗和预防的实践。在这里，我们提供了11.5年的每月治疗统计数据，显示2008年6月至2019年12月期间共摄入5127只受感染的狗，以及最近更详细的数据集，用于检查私人动物收容所大规模治疗犬细小病毒（CPV）的死亡风险，季节性和资源需求。研究期间动物的总存活率为86.6%（n= 4438/5127只犬存活），给药5天后存活概率增加至96.7%（80%的死亡发生在该期间）。观察到一个明显的细小病毒季节，在5月和6月达到高峰，在8月、9月、12月和1月达到低谷，这可能导致每月种群中有多达41只动物达到高峰至低谷（10月可能出现一个较小的季节）。低体重和雄性动物的死亡风险较高，而年龄不是一个重要的影响因素。在7天的中位治疗持续时间内，治疗时间平均为9.03小时。这些研究结果表明，犬细小病毒可以在收容所内使用主要是志愿者的劳动力以可持续的方式成功治疗。
Simple Summary The canine parvovirus (CPV) is a highly contagious gastrointestinal disease which affects unvaccinated, insufficiently vaccinated, or improperly vaccinated dogs and results in a fatality rate greater than 90% if left untreated. Treatment in private practice settings can often cost several thousand dollars, making it an unaffordable option for many pet owners as well as a challenging population to treat for shelters. Here, we examine 11.5 years of data from Austin Pets Alive!, a private animal shelter in Austin, TX, which has treated 5127 dogs infected with CPV since 2008. We show an 86.6% (n= 4438/5127) survival rate, with the most critical period of treatment during the first five days of care, and detail the protocols used to achieve this high proportion of successful treatment outcomes. A CPV season was observed peaking in May and June and accounting for as much as a 41 animal/month increase compared to low periods in August, September, December, and January. Low-weight animals and male animals were found to be at higher risk for mortality. Together, these results aim to assist shelters in creating programs to treat this disease and to inspire future research into improving practices in treatment and prevention. Here, we present 11.5 years of monthly treatment statistics showing an overall intake of 5127 infected dogs between June 2008 and December 2019, as well as more detailed datasets from more recent, less protracted time periods for the examination of mortality risk, seasonality, and resource requirements in the mass treatment of canine parvovirus (CPV) in a private animal shelter. The total survival rate of animals during the study period was 86.6% (n= 4438/5127 dogs survived) with the probability of survival increasing to 96.7% after five days of treatment (with 80% of fatalities occurring in that period). A distinct parvovirus season peaking in May and June and troughing in August, September, December, and January was observed, which could have contributed as much as 41 animals peak-to-trough in the monthly population (with a potential, smaller season occurring in October). Low-weight and male animals were at higher risk for death, whereas age was not a significant contributing factor. Treatment time averaged 9.03 h of total care during a seven-day median treatment duration. These findings, taken together, demonstrate that canine parvovirus can be successfully treated in a sustainable manner within a shelter setting using a largely volunteer workforce.