HOMOLYTIC ALKOXYCARBONYLATION REACTIONS IN 2-PHASE SYSTEMS .2. STUDIES ON THE ETHOXYCARBONYLATION OF SOME SELECTED PI-DEFICIENT N-HETEROAROMATIC SYSTEMS
HOMOLYTIC ALKOXYCARBONYLATION REACTIONS IN 2-PHASE SYSTEMS .2. STUDIES ON THE ETHOXYCARBONYLATION OF SOME SELECTED PI-DEFICIENT N-HETEROAROMATIC SYSTEMS
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DOI：
10.1016/s0040-4020(01)96080-6
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发表时间：
1986-01-01
期刊：
影响因子：
2.1
通讯作者：
LOTSCH, G
中科院分区：
文献类型：
--
作者：
HEINISCH, G;LOTSCH, G
对乙氧基羰基自由基均裂取代吡啶、喹啉和吡嗪进行了系统研究。结果表明，在适当的条件下，Minisci型烷氧基羰基化反应可以方便地制备杂芳族单羧酸酯，例如2-吡嗪甲酸烷基酯和4-烷基-2-吡啶甲酸烷基酯。
A systematic study on the homolytic substitution of pyridine, quinoline and pyrazine by ethoxycarbonyl radicals was performed. It is demonstrated that under appropriate conditions Minisci-type alkoxycarbonylation reactions can provide convenient access to heteroaromatic monocarboxylic acid esters, like alkyl 2-pyrazinecarboxylates and alkyl 4-alkyl-2-pyridinecarboxylates.