Characterization of transparent dentin in attrited teeth using optical coherence tomography
Characterization of transparent dentin in attrited teeth using optical coherence tomography
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DOI：
10.1007/s10103-014-1541-4
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发表时间：
2015-05-01
影响因子：
2.1
通讯作者：
Tagami, Junji
中科院分区：
文献类型：
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作者：
Mandurah, Mona M.;Sadr, Alireza;Tagami, Junji
随着年龄的增长，牙齿表面会发生脱落和磨损，导致牙釉质脱落，牙本质暴露和组织学改变。处理磨损的牙齿和恢复失去的组织是临床上具有挑战性的。本研究的主要目的是通过光学相干断层扫描（OCT）来表征磨损牙齿咬合面中暴露的透明牙本质。自然磨损，提取人类牙齿与咬合透明牙本质进行了研究，比较健全和龋坏的牙齿。对牙齿进行OCT成像，然后进行横切和抛光。将OCT B扫描与相同横截面的光学显微镜图像进行比较。在OCT图像中，磨损牙的透明牙本质发生了一些明显的变化。基于Beer-Lambert定律导出OCT衰减系数参数（mu（t））作为反向散射信号斜率的函数。完好、龋坏和透明牙本质的mu（t）平均值分别为1.05 +/- 0.3、2.23 +/- 0.4和0.61 +/- 0.27 mm（-1）。采用Tukey事后分析的单因素方差分析显示组间存在显著差异（p < 0.05）。透明牙本质中的生理变化涉及牙本质小管中矿物质管型的沉积，导致OCT信号的衰减较低。光学相干断层扫描技术在检测磨耗牙表面透明牙本质方面具有潜在的应用价值，可作为临床的辅助工具。
Attrition and wear of tooth surface occur with aging and result in loss of enamel, with exposure and histological changes in dentin. Dealing with attrited teeth and restoration of the lost tissue are clinically challenging. The main objective of this study is to characterize the exposed transparent dentin in the occlusal surface of attrited teeth by optical coherence tomography (OCT). Naturally attrited, extracted human teeth with occlusal-transparent dentin were investigated in comparison to sound and carious teeth. The teeth were subjected to OCT imaging and then cross-sectioned and polished. OCT B-scans were compared to light microscopy images of the same cross section. In OCT images, some changes were evident at the transparent dentin in attrited teeth. An OCT attenuation coefficient parameter (mu (t)) was derived based on the Beer-Lambert law as a function of backscatter signal slope. The mean values of mu (t) were 1.05 +/- 0.3, 2.23 +/- 0.4, and 0.61 +/- 0.27 mm(-1) for sound, carious, and transparent dentins, respectively. One-way ANOVA with Tukey's post-hoc showed a significant difference between groups (p < 0.05). Physiological changes in transparent dentin that involve deposition of mineral casts in the dentinal tubules lead to lower attenuation of OCT signal. OCT has a potential role to detect transparent dentin on the surface of attrited teeth and can be used in the future as a clinical adjunct tool.