Edentulism and Comorbid Factors
Edentulism and Comorbid Factors
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DOI：
10.1111/j.1532-849x.2009.00437.x
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发表时间：
2009-02-01
影响因子：
4
通讯作者：
Felton, David A.
中科院分区：
文献类型：
--
作者：
Felton, David A.
引言：完全性牙缺失是一个涉及生物学因素和患者相关因素的多因素过程的最终结果。它仍然是一个巨大的全球卫生保健负担，并将在可预见的未来。本综述的目的是确定存在什么样的共病因素的完全缺牙patient.Methods：本文献综述评估的文章通过美国国家医学图书馆的PubMed网站，使用关键词缺牙症的各种组合的条款共病，发病率，健康，营养，癌症，心血管健康，糖尿病，骨质疏松症，吸烟，哮喘，痴呆症，类风湿性关节炎。选择并筛选摘要，并对选定的全文文章进行综述。文章仅限于那些有足够的患者队列和最低的2年随访data.Results：无牙症被认为是一个全球性的问题，估计在未来的全口义齿的需求不断增加。完全无牙患者被发现有较高的风险，营养不良，冠状动脉斑块形成（优势比2.32），吸烟者（优势比2.42），哮喘和上颌牙弓缺牙（优势比10.52），糖尿病（优势比1.82）、类风湿性关节炎（优势比2.27）和某些癌症（优势比从1.54到2.85不等，取决于癌症的类型）。慢性残留的牙槽嵴吸收仍然是主要的口内并发症的缺齿，似乎是很少的机会，以减少骨丢失的缺齿patient.Conclusions：虽然完全缺齿的患者似乎是在多个系统性疾病的风险，这些疾病的发展是否是因果关系或偶然的尚未确定。为了最大限度地减少剩余牙槽嵴的损失，示范性全口义齿治疗，沿着建立常规召回系统，应该是该患者队列治疗的最终目标。
Introduction: Complete edentulism is the terminal outcome of a multifactorial process involving biological factors and patient-related factors. It continues to represent a tremendous global health care burden, and will for the foreseeable future. The purpose of this review is to determine what comorbid factors exist for the completely edentulous patient.Methods: This literature review evaluated articles obtained via the National Library of Medicine's PubMed Website, using keywords of edentulism with various combinations of the terms comorbidity, incidence, health, nutrition, cancer, cardiovascular health, diabetes, osteoporosis, smoking, asthma, dementia, and rheumatoid arthritis. Abstracts were selected and screened, and selected full-text articles were reviewed. Articles were limited to those with adequate patient cohorts and a minimum of 2-year follow-up data.Results: Edentulism was found to be a global issue, with estimates for an increasing demand for complete denture prostheses in the future. Completely edentulous patients were found to be at higher risk for poor nutrition, coronary artery plaque formation (odds ratio 2.32), to be smokers (odds ratio 2.42), to be asthmatic and edentulous in the maxillary arch (odds ratio 10.52), to being diabetic (odds ratio 1.82), to having rheumatoid arthritis (odds ratio 2.27), and to having certain cancers (odds ratios varying from 1.54 to 2.85, depending on the type of cancer). Chronic residual ridge resorption continues to be the primary intraoral complication of edentulation, and there appear to be few opportunities to reduce bone loss in the edentulous patient.Conclusions: While the completely edentulous patient seems to be at risk for multiple systemic disorders, whether development of these disorders is causal or casual has not been determined. To minimize the loss of residual alveolar ridges, exemplary complete denture therapy, along with the establishment of routine recall systems, should be the ultimate goal of treatment of this patient cohort.