Does the Modified Fatigue Impact Scale offer a more comprehensive assessment of fatigue in MS?
Does the Modified Fatigue Impact Scale offer a more comprehensive assessment of fatigue in MS?
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DOI：
10.1191/1352458505ms1148oa
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发表时间：
2005-01-01
影响因子：
5.8
通讯作者：
Montalbal, X
中科院分区：
文献类型：
--
作者：
Téllez, N;Río, J;Montalbal, X
背景资料：作为多发性硬化症（MS）的一种症状，疲劳是难以管理的，因为它的病因不明，缺乏疗效的药物测试日期和缺乏共识，这将是理想的措施来评估疲劳。目的：我们的目的是评估疲劳的频率在MS患者和健康对照（HC）的样本中使用两个疲劳量表，疲劳严重程度量表（FSS）和改良疲劳影响量表（MFIS）与身体，认知和心理社会分量表。我们还研究了疲劳与抑郁、残疾和干扰素β的关系。方法：354人（231名MS患者和123名HC）被纳入这项横断面研究。使用FSS和MFIS评估疲劳。采用贝克抑郁量表（BDI）测量抑郁，采用扩展残疾状态量表（EDSS）测量残疾。当FSS >= 5时，认为疲劳状态，当FSS >= 5时，认为非疲劳状态。
Background: As a symptom of multiple sclerosis (MS), fatigue is difficult to manage because of its unknown etiology, the lack of efficacy of the drugs tested to date and the absence of consensus about which would be the ideal measure to assess fatigue. Objective: Our aim was to assess the frequency of fatigue in a sample of MS patients and healthy controls (HC) using two fatigue scales, the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS) with physical, cognitive and psychosocial subscales. We also studied the relationship fatigue has with depression, disability and interferon beta. Methods: Three hundred and fifty-four individuals (231 MS patients and 123 HC) were included in this cross-sectional study. Fatigue was assessed using the FSS and MFIS. Depression was measured by the Beck Depression Inventory (BDI), and disability by the Expanded Disability Status Scale (EDSS). A status of fatigue was considered when the FSS >= 5, of non-fatigue when the FSS