Prevalence, intensity of infection and risk factors of urinary schistosomiasis in pre- school and school aged children in Guma Local Government Area, Nigeria
Prevalence, intensity of infection and risk factors of urinary schistosomiasis in pre- school and school aged children in Guma Local Government Area, Nigeria
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DOI：
10.1016/s1995-7645(13)60188-1
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发表时间：
2014-01-01
影响因子：
3.1
通讯作者：
Houmsou, R. S.
中科院分区：
文献类型：
--
作者：
Amuta, E. U.;Houmsou, R. S.
目的：了解尼日利亚贝努埃州古马地方政府辖区学龄前和学龄儿童尿路血吸虫病的流行程度、感染强度及相关危险因素。方法：采用聚碳酸酯膜过滤器尿液过滤技术对尿液标本进行处理，并测定尿中血血吸虫卵的存在。还向儿童发放了调查表，以收集有关社会人口数据和与水接触活动的资料。结果：300份尿样中总患病率为55.0%（165/300）。不同社区的感染率为36.0% ~ 64.0%，差异有统计学意义（chi(2)= 11.59， P=0.041）。男性感染率为60.6%(103/170)，女性感染率为47.7%(62/130)，差异有统计学意义（chi(2)=4.95， P=0.026）。11 ~ 15岁儿童的年龄相关患病率为70.5%(36/5)，高于1 ~ 5岁儿童的44.9%（53/118）。各年龄组间患病率差异有统计学意义（chi(2)=10.56， P=0.014）。该地区轻感染（1 ~ 49个鸡蛋/10 mL尿）患病率（86.6%）显著高于重感染（50个鸡蛋/10 mL尿）患病率（13.3%）（t=16.48， P=0.000）。儿童水接触活动结果显示，该地区参与灌溉和水体游泳的儿童感染尿路血吸虫病的风险较高，危险因素奇比分别为2.756（1.334 ~ 5.693）和2.366 （1.131 ~ 4.948）
Objective: To determine the prevalence and intensity of infection and the risk factors associated with urinary schistosomiasis in pre-school and school aged children in Guma Local Government Area of Benue State, Nigeria. Methods: Urine filtration technique using Polycarbonate membrane filters was employed to process urine specimens and to determine presence of Schistosoma haematobium eggs in urine. Questionnaires were also administered to children to collect information on socio-demographic data and water-contact activities. Results: An overall prevalence of 55.0% (165/300) was recorded out of the 300 urine samples examined. Prevalence of infection varied between 36.0%-64.0% with a significant difference (chi(2)= 11.59, P=0.041) between the different communities visited. Males were more infected (60.6%, 103/170) than females (47.7% 62/130) with a significant difference (chi(2)=4.95, P=0.026). The age-related prevalence showed higher prevalence 70.5 %, 36/5 in the 11-15 year old children than that in the 1-5 old ones (44.9%, 53/118). A significant difference was observed in the prevalence between the age groups (chi(2)=10.56, P=0.014). The prevalence of light intensity of infection (1-49 eggs/10 mL of urine) (86.6%) was significantly higher than that of heavy intensity of infection (>= 50 eggs/10 mL of urine) (13.3%) in the area (t=16.48, P=0.000). Water contact activities of the children revealed that children that were involved in irrigation and those that went swimming in water bodies were observed to be at higher risk of becoming infected with urinary schistosomiasis in the area with odd ratios (risk factors) of 2.756 (1.334-5.693) and 2.366 (1.131-4.948) respectively at P