Clincal Version of the Vascular Entoptoscope

Clincal Version of the Vascular Entoptoscope
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血管内窥镜的临床版本

DOI:
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发表时间:
1996
期刊:
Vision Science and its Applications
影响因子:
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通讯作者:
Janet J. Hendricks
Janet J. Hendricks
中科院分区:
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文献类型:
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作者:
Raul Nuñez;R. Applegate;A. Bradley;Janet J. Hendricks

文献摘要

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眼后极包括解剖上的中央窝和中央窝。这些结构高度专业化,以最大限度地提高视觉敏锐度。在中央凹中,视网膜内层到外核层被移位形成一个凹坑,凹坑中包含视网膜中最高密度的视锥细胞(每平方毫米147,000个视锥细胞)。中央凹区域的视网膜毛细血管通常形成同心排列的通道,最终形成一个直径约0.5 mm的毛细血管环,勾勒出一个无毛细血管区,称为“中央凹无血管区”FAZ(1)。包括视网膜脉管系统在内的视网膜内部结构的侧向位移可能是为了给光导部位留下通畅的光路,从而提高图像质量。由于视网膜的反向性质(血管位于入射光和光感受器之间),人类有可能看到自己视网膜血管及其内容物的阴影。内视法在19世纪被描述为视网膜血管和血流的可视化(2),最近内视可视化方法被用于研究中央凹毛细血管细节和中央凹无血管带(FAZ)的大小和形状(3-5)、中央凹血管(4,6,7)、黄斑血流(8,9)和FAZ周围的毛细血管密度(10)。
The posterior pole of the eye contains the anatomic fovea and foveola. These structures are highly specialized to maximize visual acuity. In foveola, the inner retinal layers down to the outer nuclear layer are displaced forming a pit, which contains the highest density of cones in the retina (147,000 cones per mm2). The retinal capillaries in the area of the fovea typically form concentrically arranged channels ending in a capillary loop approximately 0.5 mm across which outline a capillary-free zone known as the "foveal avascular zone" FAZ(1). The lateral displacement of inner retinal structures, including the retinal vasculature, presumably exists to leave an unobstructed light path to the site of phototransduction, thereby enhancing image quality. Because of the inverted nature of the retina (blood vessels lie between incoming light and the photoreceptors), it is possible for humans to view shadows of their own retinal vessels and their contents. Entoptic methods for their visualization of retinal blood vessels and blood flow were described in the nineteenth century(2), and recently entoptic visualization methods have been use to study the foveal capillary details and the foveal avascular zone (FAZ) size and shape (3-5), foveola vessels (4,6,7), macular blood flow (8,9) and capillary density around the FAZ (10).