Chiral Bronsted Acid Catalyzed Enantioselective Phosphonylation of Allylamine via Oxidative Dehydrogenation Coupling
Chiral Bronsted Acid Catalyzed Enantioselective Phosphonylation of Allylamine via Oxidative Dehydrogenation Coupling
复制标题
手性布朗斯台德酸催化氧化脱氢偶联烯丙胺的对映选择性磷酸化
DOI：
10.1021/acs.orglett.6b01514
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发表时间：
2016-07-01
期刊：
影响因子：
5.2
通讯作者：
Yang, Shang-Dong
中科院分区：
文献类型：
--
作者：
Cheng, Ming-Xing;Ma, Ran-Song;Yang, Shang-Dong
A new strategy for the synthesis of chiral alpha-amino phosphonates by enantioselective C-H phosphonylation of allylamine with phosphite in the presence of a chiral Bronsted acid catalyst has been developed. This protocol successfully integrates direct C-H oxidation with asymmetric phosphonylation and exhibits high enantioselectivity.
