Crimean-Congo hemorrhagic fever and expansion from endemic regions
Crimean-Congo hemorrhagic fever and expansion from endemic regions
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DOI：
10.1016/j.coviro.2018.12.002
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发表时间：
2019-02-01
影响因子：
5.9
通讯作者：
Spiropoulou, Christina F.
中科院分区：
文献类型：
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作者：
Spengler, Jessica R.;Bergeron, Eric;Spiropoulou, Christina F.
克里米亚-刚果出血热（CCHF）是一种病毒介导的出血性疾病，发生在广泛的地理区域。近年来，各种主动和被动的监测网络，提高了我们的知识与克里米亚-刚果出血热病毒（CCHFV），CCHF的病原体现有的流通领域。这些调查有助于更好地确定病毒的分布。病毒向新区域的扩散可以通过多种方式发生，包括引入受感染的人、媒介或动物。在这里，这些潜在的贡献者CCHFV扩展到邻国和地理上遥远的位置进行审查，并探讨这些事件的可能性和可能的影响，根据已知的病毒特征及其自然维护和传播周期。此外，本报告还讨论了目前描述的CCHFV分布的局限性，以及评估在新地区确定的病毒传播的挑战。
Crimean-Congo hemorrhagic fever (CCHF) is a virus-mediated hemorrhagic disease that occurs over a wide geographic region. In recent years, a variety of active and passive surveillance networks have improved our knowledge of areas with existing circulation of Crimean-Congo hemorrhagic fever virus (CCHFV), the etiologic agent of CCHF. These investigations aid in better defining the distribution of the virus. Expansion of a virus into new areas can occur through a variety of means, including introduction of infected humans, vectors, or animals. Here, these potential contributors to expansion of CCHFV into neighboring countries and geographically distant locations are reviewed, and the likelihood and possible implications of these events, based on known characteristics of the virus and its natural maintenance and transmission cycles are explored. Furthermore, this report discusses limitations in the currently described distribution of CCHFV, and the challenges in assessing viral circulation identified in a new region as geographic expansion of the virus.