Extrapulmonary tuberculosis: epidemiology and risk factors
Extrapulmonary tuberculosis: epidemiology and risk factors
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DOI：
10.1016/j.eimc.2011.03.005
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发表时间：
2011-08-01
影响因子：
2.5
通讯作者：
Sesma-Sanchez, Pascual
中科院分区：
文献类型：
--
作者：
Francisco Garcia-Rodriguez, Jose;Alvarez-Diaz, Hortensia;Sesma-Sanchez, Pascual
目的：方法：收集1991 - 2008年在美国白人中确诊的肺外结核（EPTB）病例，将其分为肺外结核（EPTB）和肺结核（PTB）。在所有病例中，63.7%在结核病专科单位接受了随访。采用标准化方案收集数据，包括：性别、年龄、卡介苗接种、与PTB患者接触、吸烟习惯、酗酒、糖尿病、免疫抑制药物/类固醇和HIV状态。比较EPTB和FTB组的这些变量。统计学分析基于逻辑回归。结果：2,161例确诊病例中，FTB 1,186例，EPTB 705例。结核病总发病率从1992年的79.9/10万下降到2008年的27.1/10万，P
Objective: To describe the epidemiology and risk factors associated with extra-pulmonary tuberculosis (EPTB).Method: Cases of tuberculosis (TB) diagnosed from 1991 to 2008 in a Caucasian population were classified as EPTB or pulmonary TB (PTB). Of all cases, 63.7% were followed up in a specialist TB unit. A standardised protocol for data collection was used, including: gender, age, BCG vaccination, contact with PTB patient, smoking habit, alcohol abuse, diabetes mellitus, immunosuppressive drugs/steroids and HIV-status. These variables were compared between EPTB and FTB groups. Statistical analysis was based on logistic regression. Odds ratios (OR) and their 95% confidence intervals (CI) were calculated.Results: Among the 2,161 cases diagnosed, 1,186 were FTB and 705 EPTB. The overall TB incidence had fallen from 79.9/100,000 in 1992 to 27.1/100.000 in 2008, P