Macular Hole following Intravitreal Bevacizumab Injection in Choroidal Neovascularization Caused by Age-Related Macular Degeneration
Macular Hole following Intravitreal Bevacizumab Injection in Choroidal Neovascularization Caused by Age-Related Macular Degeneration
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DOI：
10.1159/000319827
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发表时间：
2010-01-01
影响因子：
0.4
通讯作者：
Moisseiev, Joseph
中科院分区：
文献类型：
--
作者：
Moisseiev, Elad;Goldstein, Michaela;Moisseiev, Joseph
这份报告描述了注射贝伐单抗治疗新生血管性AMD后形成的全厚度黄斑裂孔。这种并发症可能是由于注射部位的玻璃体嵌顿或脉络膜新生血管膜收缩而对视网膜表面产生的局部牵引力所致。或者，这可能是由于贝伐单抗对先前受损的视网膜的毒性作用。
This report describes formation of a full-thickness macular hole subsequent to an injection of bevacizumab for the treatment of neovascular AMD. This complication may be caused by focal tractional forces on the retinal surface due to either vitreous incarceration at the injection site or contraction of the choroidal neovascularization membrane. Alternatively, it may be due to a toxic effect of bevacizumab on a previously compromised retina.