Accuracy of the continuous glucose monitoring system in inpatient and outpatient conditions
Accuracy of the continuous glucose monitoring system in inpatient and outpatient conditions
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DOI：
10.1016/s1262-3636(07)70023-x
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发表时间：
2003-04-01
影响因子：
7.2
通讯作者：
Selam, JL
中科院分区：
文献类型：
--
作者：
Djakouré-Platonoff, C;Radermercker, R;Selam, JL
目的：为了评估在住院和门诊条件下，仅使用非校准数据，连续葡萄糖监测系统（CG-MS）的准确性，研究设计和方法：12名21和20名1型糖尿病患者参加了3天住院，6天门诊（即，连续佩戴2个传感器）和3天门诊研究。毛细血管葡萄糖试验（7-8次/天）作为比较。成对的数据（不包括CGMS自动用于校准的4个每日对）进行了分析，使用相关系数，误差网格分析，和平均值的绝对differences.Results：三分之二和一半的感测日是合格的“最佳”，即，CGMS程序分别在住院和门诊研究中解释。住院、6天门诊和3天门诊研究的相关系数分别为0.92、0.81和0.73。98%、93%和96%的数据在A或B误差网格“临床可接受”区域中。传感器和血糖仪值之间的平均绝对差异为25 +/- 2，34 +/- 5和32 +/- 5毫克/分升。结论：CGMS可用于血糖趋势的评估，虽然准确性是更多的血糖仪的范围内，比实验室测试。住院使用提高了准确性，6天而不是3天的疗程可能更适合于评价血糖谱的每日重现性。
Objective: To evaluate in inpatient and outpatient conditions, using only non-calibration data, the accuracy of the Continuous Glucose Monitoring System,(CG-MS).Research design and methods: Twelve 21 and 20 type 1 diabetic patients participated in 3- day inhospital, 6-day ambulatory (i.e., 2 sensors worn consecutively) and 3-day ambulatory studies. Capillary glucose tests (7-8/day) served as comparisons. Pairs of data (excluding the 4 daily pairs used automatically by the CGMS for calibrations) were analyzed using correlation coefficient, error-grid analysis, and mean of absolute differences.Results: Two third and half of the sensing days were qualified as "optimal", i.e., interpretable by the CGMS program in the inpatient and outpatient studies, respectively. Correlation coefficient was 0.92, 0.81 and 0.73 in the inpatient, 6 day outpatient and 3-day outpatient studies. 98%, 93% and 96% of the data tell in the A or B error-grid "clinically acceptable" zones. Mean absolute differences between sensor and glucometer values were 25 +/- 2, 34 +/- 5 and 32 +/- 5 mg/dl.Conclusion: CGMS may be used for assessment of glycemic trends, though accuracy is more in the range of glucometers; than of laboratory tests. Inhospital utilisation improved accuracy and 6-day rather than 3-day sessions may be more appropriate to evaluate day to day reproducibility of glucose profile.