Periodic heart rate decelerations in premature infants.

Periodic heart rate decelerations in premature infants.
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DOI:
10.1258/ebm.2010.009336
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发表时间:
2010-04
期刊:
Experimental biology and medicine (Maywood, N.J.)
影响因子:
--
通讯作者:
Delos JB
Delos JB
中科院分区:
其他
文献类型:
--
作者:
Flower AA;Moorman JR;Lake DE;Delos JB

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心脏的起搏系统是复杂的;健康的心脏不断整合并对心外信号做出反应,导致高度复杂的心率模式,具有很大的变异性。然而,在实验室和一些病理或年龄相关的状态下,动力学可以显示出更容易描述和建模的降低的复杂性。降低心率复杂性既具有临床意义,也具有动力学意义--它可能提供即将到来的疾病的警告或心脏起搏系统动力学的线索。在这篇文章中,我们描述了我们在早产儿身上观察到的独特简单而有趣的心率动力学--可逆的向大幅度周期振荡的转变--我们表明,这些周期振荡的出现和消失可以用一个简单的数学模型来描述,即Hopf分叉。
The pacemaking system of the heart is complex; a healthy heart constantly integrates and responds to extracardiac signals, resulting in highly complex heart rate patterns with a great deal of variability. In the laboratory and in some pathological or age-related states, however, dynamics can show reduced complexity that is more readily described and modeled. Reduced heart rate complexity has both clinical and dynamical significance – it may provide warning of impending illness or clues about the dynamics of the heart’s pacemaking system. In this paper, we describe uniquely simple and interesting heart rate dynamics that we have observed in premature human infants -- reversible transitions to large-amplitude periodic oscillations -- and we show that the appearance and disappearance of these periodic oscillations can be described by a simple mathematical model, a Hopf bifurcation.
DOI: 10.1097/01.ccx.0000139369.65817.b6
发表时间: 2004-10-01
影响因子: 3.3
作者:
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通讯作者: Buchman, Timothy G
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