Inverse scattering for frequency-scanned full-field optical coherence tomography

Inverse scattering for frequency-scanned full-field optical coherence tomography
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DOI:
10.1364/josaa.24.001034
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发表时间:
2007-04-01
影响因子:
1.9
通讯作者:
Carney, P. Scott
Carney, P. Scott
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Marks, Daniel L.;Ralston, Tyler S.;Carney, P. Scott

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全场光学相干层析成像(OCT)能够同时成像整个散射体的表面平面,但通常是通过扫描焦点来获得三维结构。通过求解全场OCT的逆散射问题,我们证明了当焦点固定在样品内部的一个平面上时,计算重建三维体积是可能的。低数值孔径(NA) OCT系统可以容忍散焦,因为景深大,而对于高数值孔径,对散焦进行校正是至关重要的。通过推导全场OCT的反散射问题的解,我们提出并模拟了一种恢复景深内外物体结构的算法,这样即使在高NA的情况下,焦点也可以固定在样品内的特定平面上,而不会影响远离焦平面的分辨率。(c) 2007年美国光学学会。
Full-field optical coherence tomography (OCT) is able to image an entire en face plane of scatterers simultaneously, but typically the focus is scanned through the volume to acquire three-dimensional structure. By solving the inverse scattering problem for full-field OCT, we show it is possible to computationally reconstruct a three-dimensional volume while the focus is fixed at one plane inside the sample. While a low-numerical-aperture (NA) OCT system can tolerate defocus because the depth of field is large, for high NA it is critical to correct for defocus. By deriving a solution to the inverse scattering problem for full-field OCT, we propose and simulate an algorithm that recovers object structure both inside and outside the depth of field, so that even for high NA the focus can be fixed at a particular plane within the sample without compromising resolution away from the focal plane. (c) 2007 Optical Society of America.