Impact of diabetes on longevity and disability-free life expectancy among older South African adults: A prospective longitudinal analysis.

Impact of diabetes on longevity and disability-free life expectancy among older South African adults: A prospective longitudinal analysis.
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DOI:
10.1016/j.diabres.2023.110577
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发表时间:
2023-03
影响因子:
5.1
通讯作者:
Manne-Goehler, Jennifer
Manne-Goehler, Jennifer
中科院分区:
医学3区
文献类型:
--
作者:
Payne, Collin F.;Liwin, Lilipramawanty K.;Wade, Alisha N.;Houle, Brian;Du Toit, Jacques D.;Flood, David;Manne-Goehler, Jennifer

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我们试图了解人口老龄化和不断增加的糖尿病负担对南非健康长寿的共存影响。我们使用 2015 年和 2018 年“非洲健康与老龄化:南非 INDEPTH 社区的纵向研究”(HAALSI) 研究的纵向数据来探讨南非农村地区 45 岁及以上患有和不患有糖尿病的成年人的预期寿命 (LE) 和无残疾预期寿命 (DFLE)。我们使用基于马尔可夫的微观模拟根据糖尿病状态估计 LE 和 DFLE。我们发现根据糖尿病状况,剩余 LE 和 DFLE 存在明显的梯度。 45 岁时,未患糖尿病的男性的预期寿命比患有糖尿病的男性多 7.4 年 [95% CI 3.4 – 11.7],未患糖尿病的女性的预期寿命比患有糖尿病的女性多 3.9 [95% CI: 0.8 – 6.9] 年。患有糖尿病的人比没有糖尿病的人患残疾的寿命要长。我们发现南非糖尿病患者的无残疾老龄化显着减少。这一发现应该激励人们加强对老年人糖尿病及其并发症的预防和治疗工作。
We seek to understand the coexisting effects of population aging and a rising burden of diabetes on healthy longevity in South Africa. We used longitudinal data from the 2015 and 2018 waves of the “Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa” (HAALSI) study to explore life expectancy (LE) and disability-free life expectancy (DFLE) of adults aged 45 and older with and without diabetes in rural South Africa. We estimated LE and DFLE by diabetes status using Markov-based microsimulation. We find a clear gradient in remaining LE and DFLE based on diabetes status. At age 45, a man without diabetes could expect to live 7.4 [95% CI 3.4 – 11.7] more years than a man with diabetes, and a woman without diabetes could expect to live 3.9 [95% CI: 0.8 – 6.9] more years than a woman with diabetes. Individuals with diabetes lived proportionately more years subject to disability than individuals without diabetes. We find large and important decrements in disability-free aging for people with diabetes in South Africa. This finding should motivate efforts to strengthen prevention and treatment efforts for diabetes and its complications for older adults in this setting.
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