World Health Organization (WHO) risk level reductions in inpatients with alcohol use disorder and comorbid anxiety disorders.
World Health Organization (WHO) risk level reductions in inpatients with alcohol use disorder and comorbid anxiety disorders.
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世界卫生组织 (WHO) 降低了患有酒精使用障碍和共病焦虑症的住院患者的风险水平。
DOI：
10.1037/adb0000895
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Kushner,MattG
中科院分区：
文献类型：
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作者：
Stevenson,BrittanyL;Anker,Justin;Thuras,Paul;Rinehart,Linda;Kushner,MattG
研究表明，在不完全戒酒的情况下减少饮酒与改善门诊酒精使用障碍(AUD)患者的预后有关。我们试图在患有焦虑症的AUD住院患者中研究这个问题，这在AUD中是一种常见的表现。方法这是对N=241名AUD和焦虑症住院患者的随机对照试验数据的二次分析。在出院后1个月、4个月和12个月测量基线饮酒水平的变化，并在出院后4个月和12个月测量心理和功能结果。比较了三组：禁酒组、减少饮酒组(饮酒减少了1-3个世界卫生组织不戒酒的饮酒风险水平)或不减少(保持或增加饮酒风险水平)。结果在治疗后1、4和12个月，大多数患者报告戒酒(83%、63%和60%)，11%、25%和26%报告饮酒水平下降。74%的参与者在治疗后1个月实现的饮酒减少在治疗后12个月保持不变。总体而言，禁欲组在随访中报告的心理和功能结果最好，其次是减少组。减酒者和非减酒者之间的差异很小，但减酒者报告的酒精依赖严重程度和酒精相关问题明显好于非减酒者。结论尽管在这一基于戒酒的治疗样本中，戒酒与最佳结果相关，但我们得出结论，减少饮酒也与住院AUD合并焦虑障碍患者酒精相关结果的显著改善有关。在治疗后1、4和12个月，大多数患者报告戒酒(83%、63%和60%)，11%、25%和26%的患者报告饮酒水平减少。74%的参与者在治疗后1个月实现的饮酒减少在治疗后12个月保持不变。总体而言，禁欲组在随访中报告的心理和功能结果最好，其次是减少组。在减速者和非减速者之间观察到的差异很小，但减速者报告了显著的差异(心理信息数据库记录(C)2023年APA，保留所有权利)
ObjectiveStudies have demonstrated that reduced drinking without total abstinence is associated with improved outcomes in outpatients with alcohol use disorder (AUD). We sought to examine this question in AUD inpatients who have comorbid anxiety disorders, a common presentation in AUD.MethodThis is a secondary analysis of data from a randomized controlled trial for N= 241 inpatients with AUD and comorbid anxiety disorders. Change from baseline drinking level was measured at 1-, 4-, and 12-months postdischarge, and psychological and functional outcomes were measured at 4-and 12-months postdischarge. Three groups were compared: abstinent, reduced (reduced drinking by 1–3 World Health Organization drinking risk levels without abstinence), or nonreduced (maintained or increased drinking risk level).ResultsAt 1-, 4-, and 12-months posttreatment, most patients reported abstinence (83, 63, and 60%), and 11, 25, and 26% reported drinking at a reduced level. Drinking reductions achieved at 1-month posttreatment were maintained at 12-month posttreatment by 74% of participants. Overall, the abstinent group reported the best psychological and functional outcomes at follow-ups, followed by the reduced group. Few differences were observed between reducers and nonreducers, but reducers reported significantly better alcohol dependence severity and alcohol-related problems than nonreducers.ConclusionsThough abstinence was associated with the best outcomes in this abstinence-based treatment sample, we conclude that reduced drinking is also associated with significant improvements in alcohol-related outcomes in inpatients with AUD and comorbid anxiety disorders. At 1-, 4-, and 12-months posttreatment, most patients reported abstinence (83, 63, and 60%), and 11, 25, and 26% reported drinking at a reduced level. Drinking reductions achieved at 1-month posttreatment were maintained at 12-month posttreatment by 74% of participants. Overall, the abstinent group reported the best psychological and functional outcomes at follow-ups, followed by the reduced group. Few differences were observed between reducers and nonreducers, but reducers reported significantly (PsycInfo Database Record (c) 2023 APA, all rights reserved)