Modular Synthesis of Medium-Sized Fluorinated and Nonfluorinated Heterocyclic Lactones by Sequential CN-Bond-Cleaving Ring Expansion under Pd Catalysis
Modular Synthesis of Medium-Sized Fluorinated and Nonfluorinated Heterocyclic Lactones by Sequential CN-Bond-Cleaving Ring Expansion under Pd Catalysis
复制标题
Pd催化下CN键连续开环模块化合成中等大小的含氟和非氟杂环内酯
DOI：
10.1021/acscatal.0c03927
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发表时间：
2020-11
期刊：
影响因子：
12.9
通讯作者：
Hiroto Uno;Koki Kawai;M. Shiro;N. Shibata
中科院分区：
文献类型：
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作者：
Hiroto Uno;Koki Kawai;M. Shiro;N. Shibata
含氟杂环化合物和中等大小的杂环化合物在药物化学中都是很有吸引力的骨架。然而，中等大小的含氟杂环化合物的构建还有待进一步研究。
Fluoro-functionalized heterocycles and medium-sized heterocycles are both attractive skeletons in medicinal chemistry. However, the construction of medium-sized fluoro-functionalized heterocycles r...