Enhanced sensitivity of wavelength modulated surface plasmon resonance devices using dispersion from a dye solution
Enhanced sensitivity of wavelength modulated surface plasmon resonance devices using dispersion from a dye solution
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DOI：
10.1016/s0925-4005(98)00323-2
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发表时间：
1999-01-25
影响因子：
8.4
通讯作者：
Jorgenson, RC
中科院分区：
文献类型：
--
作者：
Hanning, A;Roeraade, J;Jorgenson, RC
提出了一种提高波长调制表面等离子体共振器件灵敏度的色散技术。采用1,1'3,3,3',3'-六亚甲基二碳菁（HIDC）碘化染料，该染料含有以表面等离子体共振耦合波长为中心的强吸收带，提高了对体溶液折射率的灵敏度和对传感器表面附近分析物的检测。从表面等离子体共振的基本方程出发，导出了增强效应的定量理论。给出了一种表面等离子体共振光纤传感器的实验结果。对于散装蔗糖溶液，表面等离子体共振响应的灵敏度提高了lt倍，对于蛋白质与传感器表面的结合，灵敏度提高了2倍。理论分析表明，它应该很容易获得更大的灵敏度提高。(C) 1999 Elsevier Science S.A.版权所有
A dispersion technique for enhancing the sensitivity of wavelength modulated surface plasmon resonance devices is presented. Using the dye, 1,1'3,3,3',3'-hexamethylindodicarbocyanine (HIDC) iodide, which contains a strong absorption band centered in the dynamic range of the surface plasmon resonance coupling wavelength, the sensitivity to the bulk solution refractive index and the detection of analyte near the sensor surface is increased. A quantitative theory for the enhancement effect is derived from the fundamental equation for surface plasmon resonance. Experimental results are presented for a surface plasmon resonance fiber optic sensor. As much as a Lt-fold enhancement in the sensitivity of the surface plasmon resonance response was obtained for bulk sucrose solutions, and a 2-fold enhancement was obtained for binding of proteins to the sensor surface. The theoretical analysis shows that it should readily be possible to obtain significantly greater enhancements of the sensitivity. (C) 1999 Elsevier Science S.A. All rights reserved.