Priming effects in the fusiform gyrus: changes in neural activity beyond the second presentation.
Priming effects in the fusiform gyrus: changes in neural activity beyond the second presentation.
复制标题
梭状回的启动效应：第二次呈现之后神经活动的变化。
DOI：
10.1093/cercor/bhh179
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Mesulam,M-Marsel
中科院分区：
文献类型：
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作者：
Reber,PaulJ;Gitelman,DarrenR;Parrish,ToddB;Mesulam,M-Marsel
重复启动通常会导致在第二次暴露于相同的视觉刺激时感觉皮层区域的激活减少。这种效应被认为反映了对先前看到的刺激的更有效或更流畅的再处理，从而需要更少的神经活动。流畅的再处理被假设为是一个潜在的链接，从重复启动与视觉专业知识相关的神经变化。为了研究这种潜在的联系，使用功能性磁共振成像在8次刺激重复中检查了启动的神经相关性。双侧腹侧枕颞皮层（包括梭状回）的大面积区域对第二次刺激的反应降低。这些区域中的大多数在随后重复相同刺激时没有进一步减少。由于专业知识的积累经历了多次暴露，这些区域虽然明显参与了启动，但并没有表现出与专业知识发展相一致的活动模式。与此相反，在右侧后梭状回的区域表现出减少的诱发反应，从第二次到第八次演示的刺激重复的幅度增长。该区域表现出的活动模式与跨试验的流畅性效应的逐渐和累积增强一致，这表明它可能介导了启动和视觉专业知识的发展之间的联系。
Repetition priming typically leads to a decrease in the activation of sensory cortical areas upon a second exposure to the same visual stimulus. This effect is thought to reflect more efficient or fluent re-processing of previously seen stimuli so that less neural activity is required. Fluent re-processing has been hypothesized to be a potential link from repetition priming to neural changes associated with visual expertise. To examine this potential connection, the neural correlates of priming were examined across eight stimulus repetitions using functional magnetic resonance imaging. Sizeable regions of bilateral ventral occipito-temporal cortex (including the fusiform gyrus) exhibited reduced responses to the second presentation of a stimulus. Most of these areas displayed no further reduction in response to subsequent repetitions of the same stimuli. Because expertise accrues over many exposures, these areas, while clearly involved in priming, do not exhibit an activity pattern consistent with the development of expertise. In contrast, an area in the right posterior fusiform gyrus exhibited reductions in evoked response that grew in magnitude for stimulus repetitions from the second to the eighth presentations. This region exhibits a pattern of activity consistent with a gradual and cumulative enhancement of the fluency effect across trials, suggesting that it may mediate the link between priming and the development of visual expertise.