Investigation of Mycoplasma pneumoniae infection in pediatric population from 12,025 cases with respiratory infection
Investigation of Mycoplasma pneumoniae infection in pediatric population from 12,025 cases with respiratory infection
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12025例呼吸道感染病例儿童肺炎支原体感染情况调查
DOI：
10.1016/j.diagmicrobio.2012.08.027
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发表时间：
2013-01-01
影响因子：
2.9
通讯作者：
Zou, Lin
中科院分区：
文献类型：
--
作者：
He, Xiao-yan;Wang, Xing-bin;Zou, Lin
虽然肺炎支原体(MP)是儿童非典型肺炎的主要病原体，但在大量儿童人群中MP感染的临床和实验室特征的报道较少。在此，我们同时采用血清学和聚合酶链式反应(PCR)的方法对12025例呼吸道感染住院儿童进行了回顾性分析。结果表明，2433名儿童(20.23%)感染肺炎支原体，主要发生在11~4月。咽痛和咽炎是肺炎支原体感染所特有的。儿童MP-DNA阳性率高于MP-IgM
Although Mycoplasma pneumoniae (MP) is a major pathogen of primary atypical pneumonia in children, the clinical and laboratory characteristics of MP infection in large pediatric population are less reported. Here, we retrospectively analyzed 12,025 hospitalized children with respiratory infection by using serology and polymerase chain reaction (PCR) methods simultaneously. The results showed that 2433 (20.23%) children had MP infection, which mainly occurred in November to April. The presence of sore throat and pharyngitis was peculiar to MP infection. The positive percentage of MP-DNA was higher than that of MP-IgM in children aged