STABILITY OF ENZYMES IN POST‐MORTEM RAT BRAIN 1
STABILITY OF ENZYMES IN POST‐MORTEM RAT BRAIN 1
复制标题
死后大鼠大脑中酶的稳定性 1
作者：
S. Fahn;L. Cote
在断头死亡后，在室温下保持不同时间间隔的大鼠脑中测量酶活性。酪氨酸羟化酶、单胺氧化酶、胆碱乙酰转移酶和乙酰胆碱酯酶在14小时内显示出活性的大幅下降，分别达到64、78、60和58%。零时间活动多巴脱羧酶、谷氨酸脱羧酶、乳酸脱氢酶、Na-K-ATP酶和Mg-ATP酶显示出小于15%的活性下降。研究的大多数酶的活性在人脑标本可能在死后6 - 14小时之间的时间段内变化不大，这是为了进行生化研究而获得的
Enzyme activities were measured in rat brains kept at room temperature for various intervals after death by decapitation. Tytosine hydroxylase, monoamine oxidase, choline acetyltransferase, and acetylcholinesterase show a substantial decline in activity over 14h reaching 64, 78, 60 and 58%, respectively. of the zero‐time activity. DOPA decarboxylase, glutamic acid decarboxylase, lactate dehydrogenase, Na‐K‐ATPase and Mg‐ATPase show less than a 15% decline in activity. The activities of most of the enzymes studied show little change time period when human brain specimens are likely between the 6th and 14th hour after death, the to be obtained for biochemical studies