The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA)
The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA)
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DOI：
10.1107/s2052520614026389
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发表时间：
2015-02-01
影响因子：
1.9
通讯作者：
Oswald, Iain D. H.
中科院分区：
文献类型：
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作者：
Connor, Lauren E.;Delori, Amit;Oswald, Iain D. H.
MDMA(3，4-亚甲基二氧基甲基苯丙胺)是一种A类物质，通常以片状形式存在。在环境条件下，它只在一个正交多晶型中观察到。它显示出亚甲二氧基环周围轻微的位置无序，这种无序在高达6.66 Gpa的压缩过程中持续存在。当超过传压介质的静压极限时，晶体质量在6.66 GPa以上恶化。结构经历各向异性压缩，其中a轴压缩最大(12%cf.B轴和c轴分别为4%和10%)。这是由于氢键的模式，它的作用就像一个弹簧，允许沿着这个方向压缩。
MDMA (3,4-methylenedioxymethamphetamine) is a Class A substance that is usually found in a tableted form. It is only observed in one orthorhombic polymorph under ambient conditions. It shows slight positional disorder around the methlyenedioxy ring which persists during compression up to 6.66GPa. The crystal quality deteriorates above 6.66GPa where the hydrostatic limit of the pressure-transmitting medium is exceeded. The structure undergoes anisotropic compression with the a-axis compressing the greatest (12% cf. 4 and 10% for the b- and c-axes, respectively). This is due to the pattern of the hydrogen bonding which acts like a spring and allows the compression along this direction.