Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study.
Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study.
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海地艾滋病毒患者中与抗逆转录病毒疗法遵守的因素：一项横断面研究。
DOI：
10.1186/s12981-021-00405-4
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发表时间：
2021-11-02
影响因子：
2.2
通讯作者：
Vanessa C
中科院分区：
文献类型：
--
作者：
Dorcélus L;Bernard J Jr;Georgery C;Vanessa C
社会经济、人口统计学和临床因素会影响艾滋病毒感染者（PLH）对治疗的依从性，并可能对他们的预后和生存产生影响。本研究的主要目的是评估这些因素作为海地中部接受护理的患者依从性的潜在障碍。对在海地安什圣泰蕾兹医院结核病/艾滋病诊所接受抗逆转录病毒治疗的艾滋病毒携带者进行了一项横断面研究。在2019年6月至8月的随访期间，共接触了426名潜在参与者，其中411人参与了研究。在给予知情同意后，研究参与者完成了一个结构化的访谈，其中包括自我报告项目量表（SRIS），一个标准的措施，以评估依从性。评估了社会人口统计学、经济和临床因素与依从性的关系。411名参与患者占研究期间结核/艾滋病诊所患者人群的39%。平均年龄为43.7岁（范围：19 - 80岁），65.5%为女性，78.1%仅受过小学教育。近78%的患者接受抗逆转录病毒治疗不到10年，3.41%的患者报告依从性差，28%的患者依从性低于优秀。在双变量分析中，与依从性差相关的因素是年龄小于40岁（OR：6.32，95%CI 2.04 - 10.58，p <0.01）和无法满足基本需求（OR：2.70，95%CI 1.04 - 7.0，p = 0.03）。为了提高服药依从性，医院应加强对年轻接受抗逆转录病毒治疗的患者的咨询，并提供经济援助和其他社会服务干预。应在海地其他艾滋病毒管理中心和类似情况下开展研究，以检查ART坚持的障碍，目的是改善资源有限环境中PLH的预后和长期生存。
Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence among patients receiving care in central Haiti. A cross-sectional study was conducted among PLH receiving antiretroviral therapy (ART) at the TB/HIV clinic at St. Therese Hospital in Hinche, Haiti. A total of 426 potential participants were approached during their follow-up visits from June to August 2019, of whom 411 participated in the study. After giving informed consent, study participants completed a structured interview that included the Self-Report Item Scale (SRIS), a standard measure, to assess adherence. Socio-demographic, economic and clinical factors were assessed for their association with adherence. The 411 participating patients represented 39% of the patient population at the TB/HIV clinic during the timeframe of the study. The mean age was 43.7 years (range: 19–80), 65.5% were female and 78.1% had only achieved a primary level of schooling. Nearly 78% had received ART for less than 10 years, 3.41% reported having poor adherence and 28% less than excellent adherence. Factors related to poor adherence in bivariate analysis were age less than 40 years (OR: 6.32, 95% CI 2.04–10.58, p < 0.01) and inability to meet basic needs (OR: 2.70, 95% CI 1.04–7.0, p = 0.03). To improve medication adherence, the hospital should strengthen patient counselling of younger recipients of ART and provide financial assistance and other social service interventions. Studies should be implemented in other HIV management centers in Haiti and similar contexts to examine barriers to ART adherence with the goal of improving prognosis and survival in the long-term among PLH in resource-limited setting.
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影响因子：
1.2
作者：
Anyaike, Chukwuma;Atoyebi, Oladele Ademola;Babatunde, Oluwole Adeyemi
通讯作者：
Babatunde, Oluwole Adeyemi
DOI：
10.1080/09540121.2010.525603
发表时间：
2011-01-01
影响因子：
1.7
作者：
Kyser, Melanie;Buchacz, Kate;Brooks, John T.
通讯作者：
Brooks, John T.
影响因子：
1.9
作者：
DRAINE, J;SOLOMON, P
通讯作者：
SOLOMON, P
DOI：
10.1016/s2468-2667(16)30002-0
发表时间：
2016-11
期刊：
The Lancet. Public health
影响因子：
--
作者：
Burch LS;Smith CJ;Anderson J;Sherr L;Rodger AJ;O'Connell R;Geretti AM;Gilson R;Fisher M;Elford J;Jones M;Collins S;Azad Y;Phillips AN;Speakman A;Johnson MA;Lampe FC
通讯作者：
Lampe FC
影响因子：
4.4
作者：
Malow, Robert;Devieux, Jessy G.;Pape, Jean W.
通讯作者：
Pape, Jean W.