Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba
Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba
复制标题
DOI：
10.1155/2019/2403718
复制
发表时间：
2019-06-17
影响因子：
--
通讯作者：
Alqahtani, Ali S.
中科院分区：
文献类型：
--
作者：
Khan, Waliullah;Subhan, Sidra;Alqahtani, Ali S.
研究了白花曼陀罗的叶、根、茎、花和种子部位的植物化学特性和抗氧化活性。研究还评估了重金属(铬、锰、锌和铜)在植物各部分的积累情况。在植物化学成分中，生物碱只存在于叶片中，而单宁、黄酮类和酚类化合物存在于植物的所有部位。在抗氧化活性方面，以抗坏血酸为标准，对2，2-二苯基-1-苦基肼(DPPH)进行了自由基清除实验。茎提取物在甲醇中活性较高，叶提取物在正己烷、乙酸乙酯和氯仿中活性较高。此外，所有植物部位都检测到了目标重金属，其中叶片中的锌含量最高，茎、根、花和种子中的铜含量最高。白花蛇舌草具有较强的抗氧化能力和植物化学成分，可以通过参与抗氧化防御系统来对抗自由基的产生，在药物制剂中具有重要的应用前景。
This study investigated the phytochemical characteristics and antioxidant activity in leaves, roots, stem, flower, and seed parts of Datura alba (D. alba). The study also assessed the heavy metal (Cr, Mn, Zn, and Cu) accumulation in each part of the plant. Among the phytochemicals, alkaloids were found only in leaves while tannins, flavonoids, and phenols were present in all parts of the plant. For antioxidant activity, free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) was performed using ascorbic acid as the standard. Higher activity was shown by stem extract in methanol and leaf extract in n-hexane, ethyl acetate, and chloroform. Furthermore, all the target heavy metals were detected in all plant sections with the highest concentration of Zn in leaves and Cu in stem, root, flower, and seed. Due to stronger antioxidant potential and phytochemical composition, D. alba could prove as valuable prospect in pharmaceutical formulations by taking part in the antioxidant defense system against generation of free radicals.