2-Picoline catalyst-triggered [2 + 2 + 2] cycloaddition-type reaction of acetylenedicarboxylates, aldehydes and alkenes
2-Picoline catalyst-triggered [2 + 2 + 2] cycloaddition-type reaction of acetylenedicarboxylates, aldehydes and alkenes
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2-甲基吡啶催化剂引发的乙炔二羧酸酯、醛和烯烃的[2 2 2]环加成反应
DOI：
10.1039/c8ob01774c
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发表时间：
2018
影响因子：
3.2
通讯作者：
Saito Akio
中科院分区：
文献类型：
--
作者：
Tateishi Keiichiro;Noguchi Keiichi;Saito Akio
2-甲基吡啶有效地催化在烯烃存在下由乙炔二羧酸酯和醛形成α，β-烯酮，从而以中等至良好的产率产生吡喃，具有完全的区域选择性。这种吡喃的合成方法被表示为在无金属条件下三种不同组分的催化和直接[2 + 2 + 2]环加成的第一个实例。
2-Picoline efficiently catalyzes the formation of α,β-enones from acetylenedicarboxylates and aldehydes in the presence of alkenes, thereby leading to pyrans in moderate to good yields with complete regioselectivities. This synthetic method of pyrans is represented as a first example of catalytic and direct [2 + 2 + 2] cycloaddition of three different components under the metal-free conditions.