Severe hyperkalemia following blood transfusions: Is there a link?
Severe hyperkalemia following blood transfusions: Is there a link?
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输血后严重高钾血症：有联系吗？
DOI：
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
M. Elisaf
中科院分区：
文献类型：
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作者：
C. Rizos;H. Milionis;M. Elisaf
消化道出血的病人往往需要大量输血。在输血的各种副作用中，钾水平升高是一个很严重却常被忽视的副作用。我们报告一例严重高钾血症的病人胃出血后大量输血填充红细胞。患者基线时高钾血症与接受药物治疗有关，并在低血容量后出现急性肾功能衰竭。在短时间内大量输入填充红细胞后，基线高钾血症进一步加重。提出了导致钾水平升高的相关发病机制。本文讨论了一些增加输血后高钾血症风险的危险因素。此外，适当的管理策略，预防输血相关的高钾血症也提出。医生在输血时应时刻注意高钾血症的可能性。
Patients with gastrointestinal bleeding often require large volume blood transfusion. Among the various side effects of blood transfusion, the increase of potassium levels is a serious one which is often overlooked. We report a case of severe hyperkalemia in a patient with gastric bleeding after large volume transfusion of packed red blood cells. The patient had hyperkalemia at baseline associated with his receiving medication as well as acute renal failure following hypovolemia. The baseline hyperkalemia was further aggravated after massive transfusions of packed red blood cells in a short period of time. The associated pathogenetic mechanisms resulting in the increase of potassium levels are presented. A number of risk factors which increase the risk of hyperkalemia after blood transfusion are discussed. Moreover, appropriate management strategies for the prevention of blood transfusion associated hyperkalemia are also presented. Physicians should always keep in mind the possibility of hyperkalemia in cases of blood transfusion.