The role of different K antigens of Escherichia coli in phagocytosis by polymorphonuclear leukocytes.

The role of different K antigens of Escherichia coli in phagocytosis by polymorphonuclear leukocytes.
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大肠杆菌不同K抗原在多形核白细胞吞噬作用中的作用。

DOI:
10.1099/00222615-17-2-141
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发表时间:
1984
影响因子:
3
通讯作者:
D. Maclaren
D. Maclaren
中科院分区:
医学3区
文献类型:
--
作者:
A. V. Verweij;F. Namavar;P. Peerbooms;M. Sparrius;D. Maclaren

文献摘要

被引文献

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本文研究了六株大肠杆菌K抗原与多形核白细胞(PMNL)相互作用的重要性。影响这种相互作用的主要因素是菌株在调理作用期间通过经典途径激活补体的能力,对于大多数K阳性菌株,该过程被减少。未观察到K抗原对作为真核细胞粘附物的常见皮利的功能的干扰,也未观察到K抗原对PMNL的毒性作用。
The importance of K antigens from six strains of Escherichia coli for the interaction with polymorphonuclear leukocytes (PMNL) was studied. The major factor influencing this interaction was the ability of strains to activate complement by the classical route during opsonisation, this process being reduced for most K-positive strains. Interference of K antigens with the functioning of common pili as adhesions of eukaryotic cells was not observed nor a toxic effect of K antigens on PMNL.