Progress in protein‐lipid interactions, volume 2
Progress in protein‐lipid interactions, volume 2
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蛋白质-脂质相互作用的进展，第 2 卷
DOI：
10.1016/0014-5793(86)81366-7
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发表时间：
1986
期刊：
影响因子：
3.5
通讯作者：
G. Roberts
中科院分区：
文献类型：
--
作者：
G. Roberts
脂质与膜蛋白的相互作用对于膜的结构显然很重要。此外，它们清楚地调节，甚至可能调节许多蛋白质的行为。近年来，对这些相互作用的研究引起了大量的关注，也引起了一定的争议。进步在很大程度上取决于技术的发展，因此这本优秀的书具有浓厚的方法论色彩是恰当的。前四章涉及结构技术的应用：Xr、ay 和中子衍射（Blaurock）、NMR 光谱（Dreese 和 Dratz 以及 Oldfield 等人）和傅里叶变换红外光谱（Mendelsohn 和 Mantsch）。 Oldfield 和他的同事在简短的一章中描述了他们通过多核 NMR 对细菌视紫红质进行的研究，该研究清楚地区分了“表面”和“埋藏”的氨基酸残基。本节剩下的三章
The interactions of lipids with membrane proteins are obviously important’for the structure of the membrane. In addition they clearly modulate, and perhaps regulate, the behaviour of many of the proteins. In recent years, the study of these interactions has generated a good deal of activity and a certain amount of controversy. Progress has depended strongly on technical developments, and it is thus appropriate that this excellent book has a strong methodological flavour. The first four chapters are concerned with the application of structural techniques: Xr, ay and neutron diffraction (Blaurock), NMR spectroscopy (Dreese and Dratz, and Oldfield et al.) and Fourier transform infrared spectroscopy (Mendelsohn and Mantsch). The short chapter by Oldfield and his colleagues describes their studies of bacteriorhodopsin by multinuclear NMR, which clearly differentiate ‘surface’and ‘buried’aminoacid residues. The remaining three chapters in this