Screening for cognitive deficits in Parkinson's disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrument
Screening for cognitive deficits in Parkinson's disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrument
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DOI：
10.1016/j.parkreldis.2007.06.008
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发表时间：
2008-01-01
影响因子：
4.1
通讯作者：
Kessler, Josef
中科院分区：
文献类型：
--
作者：
Kalbe, Elke;Calabrese, Pasquale;Kessler, Josef
认知和情感功能障碍是帕金森病（PD）中常见但常被忽视的症状。我们开发了筛选工具帕金森神经心理测量痴呆评估（PANDA）与五个认知任务和简短的抑郁问卷。对健康受试者和无认知障碍（PD）、轻度认知障碍（PD-MCD）或痴呆（PDD）的患者进行了检查。认知部分的特异性为91%，敏感性为90%。PDD + PD-MCD患者为77%。情绪问卷也具有较高的敏感性和特异性。我们的结论是，PANDA是一种经济，易于使用和敏感的工具，以检测在临床实践中的PD患者的神经心理功能障碍。(C)2007爱思唯尔有限公司保留所有权利。
Cognitive and affective dysfunctions are frequent but often neglected symptoms in Parkinson's disease (PD). We developed the screening tool Parkinson neuropsychometric dementia assessment (PANDA) with five cognitive tasks and a short depression questionnaire. Healthy subjects and patients without cognitive impairment (PD), mild cognitive disorder (PD-MCD), or dementia (PDD) were examined. The cognition part had a specificity of 91% and a sensitivity of 90%. for PDD and 77% for PDD plus PD-MCD patients. The mood questionnaire also had high sensitivity and specificity. We conclude that the PANDA is an economical, easy-to-use and sensitive tool to detect neuropsychological dysfunctions in PD patients in clinical practice. (C) 2007 Elsevier Ltd. All rights reserved.