EFFECT OF SHORT-TERM FOOD-DEPRIVATION ON REPRODUCTION IN FEMALE MICE

EFFECT OF SHORT-TERM FOOD-DEPRIVATION ON REPRODUCTION IN FEMALE MICE
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DOI:
10.1095/biolreprod33.3.660
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发表时间:
1985-01-01
影响因子:
3.6
通讯作者:
MARSTELLER, FA
MARSTELLER, FA
中科院分区:
生物学2区
文献类型:
--
作者:
BRONSON, FH;MARSTELLER, FA

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从处于发情期或间情期,或怀孕2天或12天,或处于哺乳期第2天或第12天开始,对CF - 1雌性小鼠进行24小时或48小时的食物剥夺。当雌性处于间情期时开始48小时的食物剥夺,排卵会延迟一周或更长时间;当食物剥夺始于发情期时,延迟时间较短。急性食物剥夺对怀孕影响很小。大多数从哺乳期第2天开始被剥夺食物的雌性会吃掉自己的幼崽,但在哺乳期第12天被剥夺食物的雌性很少这样做。这些结果是根据相互作用因素的复杂性来讨论的,这些因素决定了雌性生殖周期的每个阶段易受急性食物剥夺干扰的程度。
CF-1 female mice were subjected to 24 or 48 h of food deprivation beginning when they were in estrus or diestrus, or when they were 2 or 12 days pregnant, or on Days 2 or 12 of lactation. Ovulation was delayed by a week or more when 48 h of food deprivation was initiated when the female was in diestrus; lesser delays occurred when food deprivation began in estrus. There was little effect of acute food deprivation on pregnancy. Most females deprived of food beginning on Day 2 of lactation ate their young, but females deprived on Day 12 of lactation rarely did so. These results are discussed in terms of the complexity of interacting factors that determine the degree to which each stage of the female''s reproductive cycle is susceptible to disruption by acute food deprivation.