Regulation of appressorium development in pathogenic fungi.
Regulation of appressorium development in pathogenic fungi.
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DOI：
10.1016/j.pbi.2015.05.013
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发表时间：
2015-08
影响因子：
9.5
通讯作者：
Talbot NJ
中科院分区：
文献类型：
--
作者：
Ryder LS;Talbot NJ
附着胞发育与控制形态发生的细胞周期检查点有关。Ras GT3信号传导作用于cAMP和MAP激酶途径的上游，用于附着胞发育。黑色素并不完全与附着胞膨压产生有关。.隔膜蛋白介导的肌动蛋白重塑是附着胞功能所必需的。在附着胞感染期间发生效应子的局灶性分泌。许多植物病原真菌具有使用称为附着胞的专门感染细胞破坏其植物宿主的完整表皮的能力。这些细胞施加物理力量来破坏植物表面，或者以集中的方式部署酶来消化角质层和植物细胞壁。它们还提供了在植物感染时发生效应物局部分泌的方法。附着胞的发育与由隔蛋白GTP酶介导的肌动蛋白细胞骨架的重塑和细胞壁的快速分化有关。这些过程受植物细胞表面成分的感知和饥饿应激的调节，但也与控制感染相关发育的整体进展的细胞周期检查点有关。
Appressorium development is linked to cell cycle checkpoints controlling morphogenesis. Ras GTPase signalling acts upstream of cAMP and MAP kinase pathways for appressorium development. Melanin is not exclusively associated with appressorium turgor generation. . Septin-mediated actin re-modelling is essential for appressorium function. Focal secretion of effectors occurs during appressorium infection. Many plant pathogenic fungi have the capacity to breach the intact cuticles of their plant hosts using specialised infection cells called appressoria. These cells exert physical force to rupture the plant surface, or deploy enzymes in a focused way to digest the cuticle and plant cell wall. They also provide the means by which focal secretion of effectors occurs at the point of plant infection. Development of appressoria is linked to re-modelling of the actin cytoskeleton, mediated by septin GTPases, and rapid cell wall differentiation. These processes are regulated by perception of plant cell surface components, and starvation stress, but also linked to cell cycle checkpoints that control the overall progression of infection-related development.