Altered glucose 1,6‐bisphosphate and fructose 2,6‐biphosphate levels in low‐frequency stimulated rabbit fast‐twitch muscle
Altered glucose 1,6‐bisphosphate and fructose 2,6‐biphosphate levels in low‐frequency stimulated rabbit fast‐twitch muscle
复制标题
低频刺激兔快肌中葡萄糖 1,6-二磷酸和果糖 2,6-二磷酸水平的改变
DOI：
10.1016/0014-5793(91)80455-c
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发表时间：
1991
期刊：
影响因子：
3.5
通讯作者：
D. Pette
中科院分区：
文献类型：
--
作者：
H. Green;Juan Cadefau;D. Pette
Glucose 1,6‐bisphosphate (Glc‐1,6‐P2) and fructose 2,6‐bisphospate (Fru‐2,6‐P2) concentration display pronounced increases in rabbit fast‐twitch muscle during chronic low‐frequency stimulation. These increases are first seen after stimulation periods exceeding 3 h and reach maxima after 12–24h of stimulation (approximately 3‐fold for Glc‐1,6‐P2and 5‐fold for Fru‐2,6‐P2). Both matabolites regress to normal values after stimulation periods longer than 4 days. The fact that their increases coincide with the replenishment of glycogen after its initial depletion, could point to a role of Glc‐1,6‐P2and Fru‐2,6‐P2 in glycogen metabolism.
