The use of integrative therapies in patients with amyotrophic lateral sclerosis in shanghai, china.

The use of integrative therapies in patients with amyotrophic lateral sclerosis in shanghai, china.
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DOI:
10.1155/2013/613596
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发表时间:
2013
期刊:
Evidence-based complementary and alternative medicine : eCAM
影响因子:
--
通讯作者:
Zhou H
Zhou H
中科院分区:
其他
文献类型:
--
作者:
Pan W;Chen X;Bao J;Bai Y;Lu H;Wang Q;Liu Y;Yuan C;Li W;Liu Z;Liu J;Zhu X;Qin B;Cai D;Zhou H

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目标。目的探讨综合疗法(IT)在肌萎缩侧索硬化症(ALS)治疗中的应用现状。方法:研究方法。对上海市12所医院进行了横断面、多中心临床流行病学调查。我们调查了IT使用的类型和频率,并确定IT的使用是否与我们患者群体中的人口统计、社会或疾病特定特征相关。结果。在258名ALS患者中,共有231名(89.5%)符合研究条件,231名ALS患者中有229名(99%)报告至少使用了一种IT治疗ALS。维生素和中草药煎剂、中草药复方、推拿疗法和针灸是最常用的5种疗法。教育水平、收入和信息技术的使用之间有很强的关联性。家庭收入超过75,000 人民币(49,995美元)与多次使用IT有关,已婚患者使用IT的频率高于单身患者。使用IT的主要原因是治疗虚弱和疲劳、肌肉萎缩、肌萎缩侧索硬化症、抑郁、失眠、四肢疼痛或麻木以及与利鲁唑相关的副作用。结论。在上海的ALS患者中,IT的使用很常见。维生素和中药是最常用的附加疗法,IT在ALS中的广泛使用和基本上未经审查的使用需要更多的关注。
Objective. To investigate the current use of integrative therapies (IT) in the treatment of patients with amyotrophic lateral sclerosis (ALS). Methods. A cross-sectional, multicenter clinical epidemiological survey was conducted in 12 hospitals in Shanghai. We investigated the type and frequency of IT use and determined whether the use of IT correlated with demographic, social, or disease-specific characteristics in our patient population. Results. A total of 231 (89.5%) of 258 patients with ALS were eligible for the study and 229 (99% of all) of 231 reported the use of at least one IT for the treatment of ALS. Vitamins and Chinese herb decoctions, Chinese herb compounds, massage therapy, and acupuncture were the 5 most commonly used therapies. There was a strong association between education level, income, and use of IT. A household income of more than 75,000 RMB ($49,995) correlated with multiple IT use, and married patients used IT more often than single individuals. The main reasons for using IT were to treat weakness and fatigue, muscle atrophy, the development of ALS, depression, insomnia, limb pain or numbness, and side effects associated with Riluzole. Conclusion. The use of IT is common in patients with ALS in Shanghai. Vitamins and TCM are the most used additional therapies and the widespread and largely unexamined use of IT for ALS requires more attention.