Utility of Hair, Urine, and Self-Report to Monitor Drug Use in Research Studies including People with Schizophrenia.
Utility of Hair, Urine, and Self-Report to Monitor Drug Use in Research Studies including People with Schizophrenia.
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使用头发、尿液和自我报告来监测研究中的药物使用情况，包括精神分裂症患者。
DOI：
10.1080/15504260802084425
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发表时间：
2008
影响因子：
2.2
通讯作者：
Essock,SusanM
中科院分区：
文献类型：
--
作者：
Covell,NancyH;Essock,SusanM
我们通过表征提供的头发和尿液样本的数量以及头发、尿液和自我报告的药物使用之间的一致性，检验了药物与尿液在检测滥用药物方面的效用。在40名参与者中，39人(97.5%)提供尿液，只有31人(77.5%)同意提供头发(3人(7.5%)拒绝，6人(15%)不能提供头发)。头发比尿液和自我报告检测到更多的药物使用，尿液和自我报告的符合率达到90%或更高。毛发检测毒品使用，特别是可卡因的优势，可能需要包括毛发样本，以证明可卡因或较长追溯期内的药物使用；如果记录最近使用可卡因以外的药物，自我报告可能就足够了。
We examined the utility of drugs versus urine to detect drugs of abuse by characterizing the number of hair and urine samples provided and the agreement between hair, urine, and self-reported drug use. Of 40 participants, 39 (97.5%) provided urine, whole only 31 (77.5%) agreed to provide hair (3 (7.5%) declined, 6 (15%) were not able). Hair detected more drug use than urine and self-report, and concordance between urine and self-report was 90% or greater. The advantage of hair to detect drug use, particularly cocaine, may warrant inclusion of hair samples to document cocaine or drug use during longer retrospective periods; if documenting recent use of drugs other than cocaine, self-report may suffice.