BONE-MINERAL CONTENT AND GROWTH IN VERY-LOW-BIRTH-WEIGHT PREMATURE-INFANTS
BONE-MINERAL CONTENT AND GROWTH IN VERY-LOW-BIRTH-WEIGHT PREMATURE-INFANTS
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DOI：
10.1001/archpedi.1987.04460020069029
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发表时间：
1987-02-01
影响因子：
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通讯作者：
MCCORMICK, A
中科院分区：
文献类型：
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作者：
GREER, FR;MCCORMICK, A
据报道，极低出生体重（VLBW）婴儿合并支气管肺发育不良（BPD）是代谢性骨病和生长迟缓的高危人群。在一项前瞻性研究中，我们比较了16名患有BPD的VLBW婴儿和16名VLBW对照组婴儿第一年的生长和骨矿物质含量（BMC）。BPD组与对照组胎龄匹配（28.2±±）。0.8 vs 28.4。1.2周)和出生体重(986 +-。158 vs 1037 .+-。147克)。在最初的60天住院期间，钙、磷、维生素D和能量摄入没有差异。1岁时，BMC（104.4 .+-）无显著差异。21.4 vs 109.7。19.2 mg/cm)，重量(7440 +-。1090 vs 7420 .+-。826g)，长度(66.9 .+-。3.4 vs 67.7。3.0厘米)，或头围(45.1 .+-。1.5 vs 44.0 .+-。BPD组与对照组之间的差异为1.0 cm。与BMC的宫内曲线相比，两组骨矿化延迟。与巴布森生长曲线相比，早产儿在出生后第一年的生长也有所延迟。我们得出结论，对于我们的研究人群，除了BPD的存在或不存在之外，其他因素是导致VLBW早产儿骨矿化和生长明显延迟的原因。
It is reported that very-low-birth-weight (VLBW) infants with the complication of bronchopulmonary dysplasia (BPD) are at high risk for metabolic bone disease and growth retardation. In a prospective study, we compared growth and bone mineral content (BMC) during the first year of life in 16 VLBW infants with BPD and 16 VLBW control infants. The BPD and control groups were matched for gestational age (28.2 .+-. 0.8 vs 28.4 .+-. 1.2 weeks) and birth weight (986 .+-. 158 vs 1037 .+-. 147 g). Calcium, phosphorus, vitamin D, and energy intakes did not differ during the initial 60-day period of hospitalization. At 1 year of age, there were no significant differences in BMC (104.4 .+-. 21.4 vs 109.7 .+-. 19.2 mg/cm), weight (7440 .+-. 1090 vs 7420 .+-. 826 g), length (66.9 .+-. 3.4 vs 67.7 .+-. 3.0 cm), or head circumference (45.1 .+-. 1.5 vs 44.0 .+-. 1.0 cm) between BPD and control groups. In both groups bone mineralization was delayed compared to the intrauterine curve for BMC. Growth was also delayed compared to the growth curves of Babson for premature infants during the first year of life. We conclude that for our study population, factors other than the presence or absence of BPD are responsible for marked delays in bone mineralization and growth in VLBW premature infants.