A Quantitative Genetic Signature of Senescence in a Short-Lived Perennial Plant
A Quantitative Genetic Signature of Senescence in a Short-Lived Perennial Plant
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DOI：
10.1016/j.cub.2014.02.012
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发表时间：
2014-03
期刊：
影响因子：
9.2
通讯作者：
B. Pujol;Pascal Marrot;J. Pannell
中科院分区：
文献类型：
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作者：
B. Pujol;Pascal Marrot;J. Pannell
衰老的进化(生物体随年龄增长的生理衰退)构成了一个明显的悖论，因为它代表了自然选择未能提高生物体的生存和繁殖性能。如果自然选择随着年龄的增长变得不那么有效，这个悖论就可以得到解决，因为产后个体的死亡应该会减少达尔文适合度的影响[1，2]。大量的经验性工作与动物的这一预测是一致的，动物通过不朽的生殖系将自己的基因传递给后代。然而，这样的证据在植物中仍然缺乏，因为植物缺乏生殖系，其繁殖是分散的和模块化的，遍及整个胞体。在这里，我们为短命多年生植物宽叶硅藻衰老的遗传基础提供了实验证据。我们基于系谱的分析表明，与适合度密切相关的性状的加性遗传方差随着年龄的增长而显着增加。因此，这一结果扩展到植物中，为衰老进化理论提供了数量遗传支持。
The evolution of senescence (the physiological decline of organisms with age) poses an apparent paradox because it represents a failure of natural selection to increase the survival and reproductive performance of organisms. The paradox can be resolved if natural selection becomes less effective with age, because the death of postreproductive individuals should have diminished effects on Darwinian fitness [1, 2]. A substantial body of empirical work is consistent with this prediction for animals, which transmit their genes to progeny via an immortal germline. However, such evidence is still lacking in plants, which lack a germline and whose reproduction is diffuse and modular across the soma. Here, we provide experimental evidence for a genetic basis of senescence in the short-lived perennial plantSilene latifolia. Our pedigree-based analysis revealed a marked increase with age in the additive genetic variance of traits closely associated with fitness. This result thus extends to plants the quantitative genetic support for the evolutionary theory of senescence.