Selective Coassembly of Aromatic Amino Acids to Fabricate Hydrogels with Light Irradiation-Induced Emission for Fluorescent Imprint
Selective Coassembly of Aromatic Amino Acids to Fabricate Hydrogels with Light Irradiation-Induced Emission for Fluorescent Imprint
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DOI：
10.1002/adma.201705633
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发表时间：
2018-02-01
影响因子：
29.4
通讯作者：
Zhao, Yanli
中科院分区：
文献类型：
--
作者：
Xing, Pengyao;Chen, Hongzhong;Zhao, Yanli
控制共组装过程中的结构参数是制备多组分功能材料的关键。在这里，提出了一个概念验证的研究，以揭示芳香族氨基酸的取代基的影响，其选择性与联吡啶粘合剂共组装。借助X射线散射技术，发现在固态下的独立堆积以及-取代所带来的体积效应决定了共组装的发生。基于某些芳香族氨基酸和联吡啶单元之间的络合作用，成功地构建了性能良好的水凝胶，提供了前所未有的具有光辐射触发发光的智能材料。这种水凝胶在光照过程中没有相分离和光漂白，能够表现为荧光印迹材料。本研究为合理设计短肽的氨基酸残基以制备自组装多组分材料提供了一种合适的方法。此外，该协议是有用的，在筛选潜在的功能材料，由于不同的自组装行为。
Controlling the structural parameters in coassembly is crucial for the fabrication of multicomponent functional materials. Here a proof-of-concept study is presented to reveal the -substituent effect of aromatic amino acids on their selective coassembly with bipyridine binders. With the assistance of X-ray scattering technique, it is found that individual packing in the solid state as well as bulky effect brought by -substitution determines the occurrence of coassembly. A well-performed hydrogels based on the complexation between certain aromatic amino acids and bipyridine units are successfully constructed, providing unprecedented smart materials with light irradiation-triggered luminescence. Such hydrogels without the phase separation and photobleaching during light irradiation are able to behave fluorescent imprint materials. This study provides a suitable protocol in rationally designing amino acid residues of short peptides for fabricating self-assembled multicomponent materials. In addition, this protocol is useful in screening potential functional materials on account of diverse self-assembly behavior.