Impact of behavioural problems on spousal caregivers: A comparison between Alzheimer's disease and frontotemporal dementia
Impact of behavioural problems on spousal caregivers: A comparison between Alzheimer's disease and frontotemporal dementia
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DOI：
10.1159/000093102
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发表时间：
2006-01-01
影响因子：
2.4
通讯作者：
Verhey, Frans R. J.
中科院分区：
文献类型：
--
作者：
de Vugt, Marjolein E.;Riedijk, Samantha R.;Verhey, Frans R. J.
背景：行为改变是区分额颞叶痴呆（FTD）和阿尔茨海默病（AD）的关键因素，然而，人们对这些变化对照顾者的影响知之甚少。本研究的目的是比较照顾者的痛苦与AD和FTD行为症状的关系。方法：连续转诊AD患者的配偶照护者47人，FTD患者的配偶照护者27人。用神经精神量表测量患者的行为障碍和照顾者的情绪反应。结果：FTD患者的躁动、冷漠、去抑制和异常运动行为水平明显高于AD患者。FTD患者的照顾者在去抑制、抑郁和冷漠方面的痛苦得分较高，而AD患者的照顾者报告的患者冷漠、抑郁和焦虑是严重的痛苦。FTD组去抑制的平均痛苦评分较高。此外，FTD患者的护理人员报告了更高水平的一般负担，并且感觉能力低于AD护理人员。结论：总体而言，FTD患者的照顾者比AD患者的照顾者对其伴侣的行为更焦虑。这项研究的发现强调了在关注照顾者对问题行为的反应时区分诊断组和特定行为域的重要性。版权所有(C) 2006 S. Karger AG，巴塞尔
Background: Behavioural changes are a key factor in distinguishing frontotemporal dementia (FTD) from Alzheimer's disease ( AD), however, little is known about the impact of these changes on caregivers. The aim of this study was to compare caregivers' distress related to behavioural symptoms of AD and FTD. Methods: 47 spouse caregivers of consecutively referred patients with AD and 27 spouse caregivers of patients with FTD participated in this study. Behavioural disturbances in the patient and caregivers' emotional reactions were measured with the Neuropsychiatric Inventory. Results: Patients with FTD had significantly higher levels of agitation, apathy, disinhibition and aberrant motor behaviour than did patients with AD. High distress scores were found for disinhibition, depression and apathy in caregivers of FTD patients whereas caregivers of AD patients reported patient apathy, depression and anxiety as being severely distressing. Higher mean distress scores were found for disinhibition in the FTD group. Furthermore, caregivers of FTD patients reported higher levels of general burden, and felt less competent than AD caregivers. Conclusions: Caregivers of FTD patients were overall more distressed by the behaviour of their partners than were the caregivers of AD patients. Findings from this study underscore the importance of differentiating between diagnostic groups and specific behavioural domains when focusing on caregiver reactions to problem behaviour. Copyright (C) 2006 S. Karger AG, Basel.